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Aamar A, Madhani K, Anwar MS, et al. Whipple's Disease Manifested as Recurrent Ascites. Cureus. 2017;9(3):e1108doi: 10.7759/cureus.1108.
Aamar, A., Madhani, K., Anwar, M. S., Singh, P., & Garsten, J. (2017). Whipple's Disease Manifested as Recurrent Ascites. Cureus, 9(3), e1108. https://doi.org/10.7759/cureus.1108
Aamar, Ali, et al. "Whipple's Disease Manifested as Recurrent Ascites." Cureus vol. 9,3 (2017): e1108. doi: https://doi.org/10.7759/cureus.1108
Aamar A, Madhani K, Anwar MS, Singh P, Garsten J. Whipple's Disease Manifested as Recurrent Ascites. Cureus. 2017 Mar 21;9(3):e1108. doi: 10.7759/cureus.1108. PMID: 28439483; PMCID: PMC5400514.
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Cureus. 2017 Mar 21;9(3):e1108. doi: 10.7759/cureus.1108.

Whipple's Disease Manifested as Recurrent Ascites.

Cureus

Ali Aamar, Kamraan Madhani, Muhammad S Anwar, Prabhdeep Singh, Joel Garsten

Affiliations

  1. Internal Medicine, Yale Waterbury.
  2. Gastroenterology, Waterbury Hospital.

PMID: 28439483 PMCID: PMC5400514 DOI: 10.7759/cureus.1108

Abstract

Whipple's disease commonly presents as chronic diarrhea and abdominal pain. Ascites is an uncommon presentation of Whipple's disease. Here, we report a rare case of a 47-year-old male who presented with diarrhea and abdominal distention for three months. The physical examination was significant for ascites. Serum albumin was low and serum-to-ascites albumin gradient was < 1.1 g/dl. This suggested that ascites was less likely to be present due to portal hypertension. Enteroscopy showed erythematous duodenum and jejunum; biopsy was suggestive of periodic acid-Schiff stain (PAS) positive macrophages consistent with Whipple's disease. During the hospital course, the patient improved with intravenous (IV) ceftriaxone.

Keywords: ascites; small intestine; whipple’s disease

Conflict of interest statement

The authors have declared that no competing interests exist.

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