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Evid Based Complement Alternat Med. 2017;2017:8671271. doi: 10.1155/2017/8671271. Epub 2017 Mar 20.

PC2 Ovotransferrin: Characterization and Alternative Immunotherapeutic Activity.

Evidence-based complementary and alternative medicine : eCAM

Constantin Chiurciu, Viorica Chiurciu, Mariana Oporanu, Ionel Victor Pătrașcu, Iuliana Mihai, Mădălina Tablică, Romeo Teodor Cristina

Affiliations

  1. S.C. Romvac Company S.A., Soseaua Centurii 7, Voluntari, 77190 Ilfov, Romania.
  2. Department of Pharmacology and Pharmacy, Faculty of Veterinary Medicine, Banat's University of Agriculture and Veterinary Medicine "King Michael I of Romania" from Timi?oara, 119 Calea Aradului, 300645 Timi?oara, Romania.

PMID: 28408944 PMCID: PMC5376941 DOI: 10.1155/2017/8671271

Abstract

Characterization and evaluation of immunotherapeutic potential of ovotransferrin PC2 (OTf PC2) were performed in this study. The ovoprotein was obtained from egg white from hens immunized with bacterial antigens, pathogenic for humans. For the negative control samples, OTf was extracted from eggs collected from Specific Pathogen-Free (SPF) hens and purified by affinity chromatography on Protein G-agarose column with two eluting peaks: I, representing ovalbumin, and II, ovotransferrin. The final

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