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Front Med (Lausanne). 2017 Mar 22;4:32. doi: 10.3389/fmed.2017.00032. eCollection 2017.

Male Sexual Dysfunction and Chronic Kidney Disease.

Frontiers in medicine

Matthew M Edey

Affiliations

  1. Department of Nephrology, Hull and East Yorkshire Hospitals NHS Trust, Kingston upon Hull, UK; Hull-York Medical School, Kingston upon Hull, UK.

PMID: 28382300 PMCID: PMC5360730 DOI: 10.3389/fmed.2017.00032

Abstract

Male sexual dysfunction is common in chronic kidney disease (CKD), particularly in end-stage renal disease. Historically, this cause of considerable morbidity has been under-reported and under-recognized. The ideal approach to diagnosis and management remains unclear due to a paucity of good quality data, but an understanding of the pathophysiology is necessary in order to address the burden of this important complication of CKD. This paper will review the endocrine dysfunction that occurs in renal disease, particularly the hypothalamic-pituitary-gonadal axis, discuss the causes of erectile dysfunction, infertility, and altered body image and libido in these patients and suggest appropriate treatment interventions.

Keywords: chronic kidney disease; erectile dysfunction; hypogonadism; sexual dysfunction; testosterone

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