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Saudi J Anaesth. 2017 Apr-Jun;11(2):144-151. doi: 10.4103/1658-354X.203018.

Renal water conservation determines the increase in body weight after surgery: A randomized, controlled trial.

Saudi journal of anaesthesia

Robert G Hahn

Affiliations

  1. Department of Patient Safety and Quality, Research Unit, Södertälje Hospital, Södertälje, Sweden.

PMID: 28442951 PMCID: PMC5389231 DOI: 10.4103/1658-354X.203018

Abstract

BACKGROUND: The present study was undertaken to identify factors that correlate with the gain in body weight after surgery.

METHODS: Twenty-one patients (median age of 49 years) were randomized to receive either Ringer × s acetate or 6% dextran 70 as their first infusion fluid during cholecystectomy or hysterectomy. Each patient's body weight was measured before the surgery and on the first postoperative morning. Blood and urine samples were analyzed for signs of stress, inflammation, and kidney injury. The fluid retention index (FRI), which reflects how strongly the kidneys excrete or retain fluid, was also calculated.

RESULTS: The body weight increased by a median of 0.4 kg in the crystalloid fluid group and by 1.0 kg in the colloid fluid group (maximum 2.5 kg,

CONCLUSION: How strongly the kidneys excrete or retain fluid, which can be assessed by urine sampling, was the strongest indicator of the increase in body weight during the day of surgery. The amount of fluid alone did not correlate with the gain in body weight.

Keywords: C-reactive protein; fluid balance; fluid retention; neutrophil gelatinase-associated lipocalin; surgery

Conflict of interest statement

There are no conflicts of interest.

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