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Front Hum Neurosci. 2017 Apr 28;11:208. doi: 10.3389/fnhum.2017.00208. eCollection 2017.

Addiction as an Attachment Disorder: White Matter Impairment Is Linked to Increased Negative Affective States in Poly-Drug Use.

Frontiers in human neuroscience

Human-Friedrich Unterrainer, Michaela Hiebler-Ragger, Karl Koschutnig, Jürgen Fuchshuber, Sebastian Tscheschner, Maria Url, Jolana Wagner-Skacel, Eva Z Reininghaus, Ilona Papousek, Elisabeth M Weiss, Andreas Fink

Affiliations

  1. Institute of Psychology, University of GrazGraz, Austria.
  2. Center for Integrative Addiction Research, Grüner Kreis SocietyVienna, Austria.
  3. Department of Psychiatry and Psychotherapeutic Medicine, Medical University GrazGraz, Austria.
  4. Department of Medical Psychology and Psychotherapy, Medical University GrazGraz, Austria.

PMID: 28503141 PMCID: PMC5408064 DOI: 10.3389/fnhum.2017.00208

Abstract

Substance use disorders (SUD) have been shown to be linked to various neuronal and behavioral impairments. In this study, we investigate whether there is a connection between the integrity of white matter (WM) and attachment styles as well as different affective states including spirituality in a group of patients diagnosed for poly-drug use disorder (PUD) in comparison to non-clinical controls. A total sample of 59 right-handed men, comprising the groups of patients with PUD (

Keywords: DTI; affectivity; attachment; spirituality; substance misuse; white matter integrity

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