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Hilsch M, Haralampiev I, Müller P, et al. Membrane properties of hydroxycholesterols related to the brain cholesterol metabolism. Beilstein J Org Chem. 2017;13:720-727doi: 10.3762/bjoc.13.71.
Hilsch, M., Haralampiev, I., Müller, P., Huster, D., & Scheidt, H. A. (2017). Membrane properties of hydroxycholesterols related to the brain cholesterol metabolism. Beilstein journal of organic chemistry, 13720-727. https://doi.org/10.3762/bjoc.13.71
Hilsch, Malte, et al. "Membrane properties of hydroxycholesterols related to the brain cholesterol metabolism." Beilstein journal of organic chemistry vol. 13 (2017): 720-727. doi: https://doi.org/10.3762/bjoc.13.71
Hilsch M, Haralampiev I, Müller P, Huster D, Scheidt HA. Membrane properties of hydroxycholesterols related to the brain cholesterol metabolism. Beilstein J Org Chem. 2017 Apr 18;13:720-727. doi: 10.3762/bjoc.13.71. eCollection 2017. PMID: 28503207; PMCID: PMC5405690.
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Beilstein J Org Chem. 2017 Apr 18;13:720-727. doi: 10.3762/bjoc.13.71. eCollection 2017.

Membrane properties of hydroxycholesterols related to the brain cholesterol metabolism.

Beilstein journal of organic chemistry

Malte Hilsch, Ivan Haralampiev, Peter Müller, Daniel Huster, Holger A Scheidt

Affiliations

  1. Department of Biology, Humboldt University Berlin, Invalidenstraße 43, D-10115 Berlin, Germany.
  2. Institute for Medical Physics and Biophysics, Leipzig University, Härtelstr. 16-18, D-04107 Leipzig, Germany.

PMID: 28503207 PMCID: PMC5405690 DOI: 10.3762/bjoc.13.71

Abstract

Compared to cholesterol, hydroxycholesterols contain an additional hydroxy group in the alkyl chain and are able to efficiently cross the brain-blood barrier. Therefore, they are responsible for the sterol transfer between brain and circulation. The current study compares the membrane properties of several hydroxycholesterols with those of cholesterol using

Keywords: NMR; cholesterol; fluorescence; hydroxycholesterol; membrane structure

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