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J Anaesthesiol Clin Pharmacol. 2017 Jan-Mar;33(1):97-101. doi: 10.4103/joacp.JOACP_313_15.

Comparison of sevoflurane and propofol for laryngeal mask airway insertion and pressor response in patients undergoing gynecological procedures.

Journal of anaesthesiology, clinical pharmacology

Shirishkumar Gulabrao Chavan, Surita Mandhyan, Sandhya Haridas Gujar, Gourish Prakash Shinde

Affiliations

  1. Department of Anaesthesiology, ESIC Medical College and PGIMSR, KK Nagar, Chennai, Tamil Nadu, India.
  2. Department of Anaesthesiology, LTMMC, Sion, Mumbai, Maharashtra, India.
  3. Department of Anaesthesiology, ESIC-PGIMSR, Andheri, Mumbai, Maharashtra, India.
  4. Department of Cardiothoracic Anaesthesia, Seth GSMC and KEM Hospital, Mumbai, Maharashtra, India.

PMID: 28413280 PMCID: PMC5374839 DOI: 10.4103/joacp.JOACP_313_15

Abstract

BACKGROUND AND AIMS: A popular method of providing anesthesia for laryngeal mask airway (LMA) insertion is with the use of propofol. However, bolus propofol has been associated with adverse effects such as hypotension, apnea and pain on injection. Hence, time is needed to search an alternative. We aimed to compare the induction characteristics, ease of LMA insertion, hemodynamic changes and complications with inhalation of 8% sevoflurane vital capacity breath and propofol.

MATERIAL AND METHODS: A prospective randomized study of 60 American Society of Anesthesiologists' Grade I and II patients was conducted and distributed among two groups with 30 each undergoing gynecological procedures under general anesthesia. Group

RESULTS: Sevoflurane took a longer time for induction and for LMA insertion than propofol. There was no statistically significant difference between the two groups, with respect to LMA insertion characteristics, heart rate, mean arterial pressure. It is concluded that sevoflurane is associated with good hemodynamic stability and may prove useful incases where propofol is to be avoided. However, the ease of insertion provided with propofol is better.

Keywords: Hemodynamic changes; laryngeal mask airway; propofol; sevoflurane

Conflict of interest statement

There are no conflicts of interest.

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