Display options
Cite
Parsons PJ, Jones DR, Walsh LJ, et al. An Approach to the Core of Lactonamycin. Org Lett. 2017;19(10):2533-2535doi: 10.1021/acs.orglett.7b00902.
Parsons, P. J., Jones, D. R., Walsh, L. J., Allen, L. A. T., Onwubiko, A., Preece, L., Board, J., & White, A. J. P. (2017). An Approach to the Core of Lactonamycin. Organic letters, 19(10), 2533-2535. https://doi.org/10.1021/acs.orglett.7b00902
Parsons, Philip J, et al. "An Approach to the Core of Lactonamycin." Organic letters vol. 19,10 (2017): 2533-2535. doi: https://doi.org/10.1021/acs.orglett.7b00902
Parsons PJ, Jones DR, Walsh LJ, Allen LAT, Onwubiko A, Preece L, Board J, White AJP. An Approach to the Core of Lactonamycin. Org Lett. 2017 May 19;19(10):2533-2535. doi: 10.1021/acs.orglett.7b00902. Epub 2017 Apr 26. PMID: 28445072.
Copy Download .nbib Format: NLM
Share it on

Org Lett. 2017 May 19;19(10):2533-2535. doi: 10.1021/acs.orglett.7b00902. Epub 2017 Apr 26.

An Approach to the Core of Lactonamycin.

Organic letters

Philip J Parsons, Daniel R Jones, Lee J Walsh, Lewis A T Allen, Ada Onwubiko, Lewis Preece, Johnathan Board, Andrew J P White

Affiliations

  1. Department of Chemistry, Imperial College London , South Kensington, London SW7 2AZ, U.K.
  2. Department of Chemistry, University of Sussex , Falmer, Brighton BN1 9RH, U.K.

PMID: 28445072 DOI: 10.1021/acs.orglett.7b00902

Abstract

A cascade reaction has been developed for the synthesis of lactonamycin. In this paper, we demonstrate that a transition-metal-free thermal ene-diyne cyclization can be used for the construction of the entire core of the antibiotic lactonamycin and anticancer agent lactonamycin Z.

Publication Types