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J Audiol Otol. 2017 Apr;21(1):9-15. doi: 10.7874/jao.2017.21.1.9. Epub 2017 Mar 30.

Prognostic Factors for Recovery from Sudden Sensorineural Hearing Loss: A Retrospective Study.

Journal of audiology & otology

Woo Seok Kang, Chan Joo Yang, Myungjoo Shim, Chan Il Song, Tae Su Kim, Hyun Woo Lim, Joong Ho Ahn, Hong Ju Park, Jong Woo Chung

Affiliations

  1. Department of Otorhinolaryngology-Head & Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
  2. Department of Otorhinolaryngology, Hallym Hospital, Incheon, Korea.
  3. Department of Otolaryngology-Head and Neck Surgery, Jeju National University School of Medicine, Jeju, Korea.
  4. Department of Otolaryngology, Kangwon National University School of Medicine, Chuncheon, Korea.
  5. Department of Otolaryngology, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea.

PMID: 28417102 PMCID: PMC5392005 DOI: 10.7874/jao.2017.21.1.9

Abstract

BACKGROUND AND OBJECTIVES: This study aimed to investigate prognostic factors in patients with idiopathic sudden sensorineural hearing loss (ISSNHL).

SUBJECTS AND METHODS: From January 2007 to December 2011, a retrospective chart review identified 494 consecutive patients with ISSNHL. Demographic, audiometric, and clinical data were analyzed using a logistic regression test.

RESULTS: Hearing recovery from ISSNHL was significantly associated with factors such as age, duration from onset of symptoms to commencement of treatment, severity of the initial pure tone threshold, and the treatment method. Intratympanic (IT) steroid administration alone showed a comparable efficiency to oral steroid administration with or without IT steroid injection. In patients who received IT steroid injection, the duration from onset to treatment, severity of initial hearing loss, and sequential IT steroid injection following systemic steroid administration were statistically associated with hearing improvement.

CONCLUSIONS: Age, severity of initial pure tone threshold, duration from onset to treatment, initial speech discrimination, and initial pure tone threshold are statistically significant prognostic factors related to hearing improvement in ISSNHL. IT steroid injection as an initial single treatment is comparable to systemic oral steroid administration.

Keywords: Corticosteroid; Hearing; Idiopathic sudden sensorineural hearing loss; Prognosis

Conflict of interest statement

Conflicts of interest: The authors have no financial conflicts of interest.

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