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Wang B, Wang Y, Wu Q, et al. Effects of α2A Adrenoceptors on Norepinephrine Secretion from the Locus Coeruleus during Chronic Stress-Induced Depression. Front Neurosci. 2017;11:243doi: 10.3389/fnins.2017.00243.
Wang, B., Wang, Y., Wu, Q., Huang, H. P., & Li, S. (2017). Effects of α2A Adrenoceptors on Norepinephrine Secretion from the Locus Coeruleus during Chronic Stress-Induced Depression. Frontiers in neuroscience, 11243. https://doi.org/10.3389/fnins.2017.00243
Wang, Bin, et al. "Effects of α2A Adrenoceptors on Norepinephrine Secretion from the Locus Coeruleus during Chronic Stress-Induced Depression." Frontiers in neuroscience vol. 11 (2017): 243. doi: https://doi.org/10.3389/fnins.2017.00243
Wang B, Wang Y, Wu Q, Huang HP, Li S. Effects of α2A Adrenoceptors on Norepinephrine Secretion from the Locus Coeruleus during Chronic Stress-Induced Depression. Front Neurosci. 2017 May 01;11:243. doi: 10.3389/fnins.2017.00243. eCollection 2017. PMID: 28507504; PMCID: PMC5410613.
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Front Neurosci. 2017 May 01;11:243. doi: 10.3389/fnins.2017.00243. eCollection 2017.

Effects of α2A Adrenoceptors on Norepinephrine Secretion from the Locus Coeruleus during Chronic Stress-Induced Depression.

Frontiers in neuroscience

Bin Wang, Ying Wang, Qiong Wu, Hong-Ping Huang, Shao Li

Affiliations

  1. Liaoning Provincial Key Laboratory of Cerebral Diseases, Department of Physiology, Dalian Medical UniversityDalian, China.
  2. Department of Physiology and Neurobiology, Wannan Medical CollegeWuhu, China.
  3. Department of Cardiology, Institute of Heart and Vessel Diseases of Dalian Medical University, The Second Affiliated Hospital of Dalian Medical UniversityDalian, China.

PMID: 28507504 PMCID: PMC5410613 DOI: 10.3389/fnins.2017.00243

Abstract

Chronic stressors can often lead to the development of psychological disorders, such as depression and anxiety. The locus coeruleus (LC) is a stress sensitive brain region located in the pons, with noradrenergic neurons that project to the hypothalamus, especially the paraventricular nucleus (PVN) of the hypothalamus. The purpose of this paper is to better understand how alpha 2A-adrenoceptors (α

Keywords: depression; hypothalamus; locus coeruleus; norepinephrine; α2A-ardrenergic receptor

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