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Clin Psychopharmacol Neurosci. 2017 May 31;15(2):181-183. doi: 10.9758/cpn.2017.15.2.181.

Dose Dependent Course of Hyperprolactinemic and Normoprolactinemic Galactorrhea Induced by Venlafaxine.

Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology

Mehmet Akif Camkurt, Gizem Gülpamuk, Ebru Fındiklı, Rengin Elve

Affiliations

  1. Department of Psychiatry, Af?in State Hospital, Af?in, Turkey.
  2. Department of Psychiatry, Selçuk University School of Medicine, Selçuk, Turkey.
  3. Department of Psychiatry, Kahramanmara? Sütçü ?mam University, Kahramanmara?, Turkey.
  4. Department of Internal Medicine, Af?in State Hospital, Af?in, Turkey.

PMID: 28449567 PMCID: PMC5426493 DOI: 10.9758/cpn.2017.15.2.181

Abstract

Venlafaxine is a serotonergic and noradrenergic reuptake inhibitor which is used for the treatment of depression. We report a case of galactorrhea in a patient with major depressive disorder after starting treatment with venlafaxine. In particular, we discuss the course of hyper and normoprolactinemic galactorrhea. We managed this side effect initially by dose reduction and further by switching to essitalopram. Physicians should be aware of endocrinologic side effects such as galactorrhea during the serotonin and noradrenaline reuptake inhibitor treatment.

Keywords: Depression; Galactorrhea; Management; Prolactin; Therapeutics; Venlafaxine hydrochloride

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