CEN Case Rep. 2016 May;5(1):23-25. doi: 10.1007/s13730-015-0183-0. Epub 2015 Nov 24.
CEN case reports
N Bennani Guebessi, M Karkouri
PMID: 28509177 PMCID: PMC5411656 DOI: 10.1007/s13730-015-0183-0
Karyomegalic interstitial nephritis is a singular type of progressive chronic interstitial nephritis. The pathogenesis of this disease is unknown. The present study reported the case of a 22-year-old man who presented with a long history of recurrent upper respiratory tract infection episodes secondary to bronchiectasis and with progressive renal failure. Renal biopsy revealed chronic tubulointerstitial nephritis and a surprisingly marked karyomegaly specifically of the tubular epithelium.
Keywords: Interstitial nephritis; Karyomegaly; Renal failure