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Balycheva M, Faggian G, Glukhov AV, et al. Microdomain-specific localization of functional ion channels in cardiomyocytes: an emerging concept of local regulation and remodelling. Biophys Rev. 2015;7(1):43-62doi: 10.1007/s12551-014-0159-x.
Balycheva, M., Faggian, G., Glukhov, A. V., & Gorelik, J. (2015). Microdomain-specific localization of functional ion channels in cardiomyocytes: an emerging concept of local regulation and remodelling. Biophysical reviews, 7(1), 43-62. https://doi.org/10.1007/s12551-014-0159-x
Balycheva, Marina, et al. "Microdomain-specific localization of functional ion channels in cardiomyocytes: an emerging concept of local regulation and remodelling." Biophysical reviews vol. 7,1 (2015): 43-62. doi: https://doi.org/10.1007/s12551-014-0159-x
Balycheva M, Faggian G, Glukhov AV, Gorelik J. Microdomain-specific localization of functional ion channels in cardiomyocytes: an emerging concept of local regulation and remodelling. Biophys Rev. 2015 Mar;7(1):43-62. doi: 10.1007/s12551-014-0159-x. Epub 2015 Jan 15. PMID: 28509981; PMCID: PMC5425752.
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Biophys Rev. 2015 Mar;7(1):43-62. doi: 10.1007/s12551-014-0159-x. Epub 2015 Jan 15.

Microdomain-specific localization of functional ion channels in cardiomyocytes: an emerging concept of local regulation and remodelling.

Biophysical reviews

Marina Balycheva, Giuseppe Faggian, Alexey V Glukhov, Julia Gorelik

Affiliations

  1. Department of Cardiovascular Sciences, National Heart and Lung Institute, Imperial Centre for Translational and Experimental Medicine, Imperial College London, 4th Floor National Heart and Lung Institute, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK.
  2. Cardiosurgery Department, University of Verona School of Medicine, Verona, Italy.
  3. Department of Cardiovascular Sciences, National Heart and Lung Institute, Imperial Centre for Translational and Experimental Medicine, Imperial College London, 4th Floor National Heart and Lung Institute, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK. [email protected].
  4. Department of Cardiovascular Sciences, National Heart and Lung Institute, Imperial Centre for Translational and Experimental Medicine, Imperial College London, 4th Floor National Heart and Lung Institute, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK. [email protected].

PMID: 28509981 PMCID: PMC5425752 DOI: 10.1007/s12551-014-0159-x

Abstract

Cardiac excitation involves the generation of action potential by individual cells and the subsequent conduction of the action potential from cell to cell through intercellular gap junctions. Excitation of the cellular membrane results in opening of the voltage-gated L-type calcium ion (Ca

Keywords: Cardiomyocyte; Caveolae; Intercalated disc; Ion channel; Scanning ion conductance microscopy; T-tubule

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