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Ji L, Qian M, Wu N, et al. Significance of combined detection of JAK2V617F, MPL and CALR gene mutations in patients with essential thrombocythemia. Exp Ther Med. 2017;13(3):947-951doi: 10.3892/etm.2017.4077.
Ji, L., Qian, M., Wu, N., & Wu, J. (2017). Significance of combined detection of JAK2V617F, MPL and CALR gene mutations in patients with essential thrombocythemia. Experimental and therapeutic medicine, 13(3), 947-951. https://doi.org/10.3892/etm.2017.4077
Ji, Liying, et al. "Significance of combined detection of JAK2V617F, MPL and CALR gene mutations in patients with essential thrombocythemia." Experimental and therapeutic medicine vol. 13,3 (2017): 947-951. doi: https://doi.org/10.3892/etm.2017.4077
Ji L, Qian M, Wu N, Wu J. Significance of combined detection of JAK2V617F, MPL and CALR gene mutations in patients with essential thrombocythemia. Exp Ther Med. 2017 Mar;13(3):947-951. doi: 10.3892/etm.2017.4077. Epub 2017 Jan 23. PMID: 28450924; PMCID: PMC5403657.
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Exp Ther Med. 2017 Mar;13(3):947-951. doi: 10.3892/etm.2017.4077. Epub 2017 Jan 23.

Significance of combined detection of JAK2V617F, MPL and CALR gene mutations in patients with essential thrombocythemia.

Experimental and therapeutic medicine

Liying Ji, Mengyao Qian, Nana Wu, Jianmin Wu

Affiliations

  1. Institute of Genomic Medicine, Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.

PMID: 28450924 PMCID: PMC5403657 DOI: 10.3892/etm.2017.4077

Abstract

The aim of this study was to analyze the mutation rate of JAK2V617F, MPLW515L/K and CALR genes in adult patients with essential thrombocythemia (ET) and the accuracy of the combined detection by the receiver operating curve. Three hundred and forty-two cases with high-platelets (≥300×10

Keywords: CALR; JAK2V617F; MPLW515L/K; gene mutation; primary thrombocytopenia; receiver operating curve

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