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De Lacorte Singulani J, De Fátima Da Silva J, Gullo FP, et al. Preliminary evaluation of circulating microRNAs as potential biomarkers in paracoccidioidomycosis. Biomed Rep. 2017;6(3):353-357doi: 10.3892/br.2017.849.
De Lacorte Singulani, J., De Fátima Da Silva, J., Gullo, F. P., Costa, M. C., Fusco-Almeida, A. M., Enguita, F. J., & Mendes-Giannini, M. J. S. (2017). Preliminary evaluation of circulating microRNAs as potential biomarkers in paracoccidioidomycosis. Biomedical reports, 6(3), 353-357. https://doi.org/10.3892/br.2017.849
De Lacorte Singulani, Junya, et al. "Preliminary evaluation of circulating microRNAs as potential biomarkers in paracoccidioidomycosis." Biomedical reports vol. 6,3 (2017): 353-357. doi: https://doi.org/10.3892/br.2017.849
De Lacorte Singulani J, De Fátima Da Silva J, Gullo FP, Costa MC, Fusco-Almeida AM, Enguita FJ, Mendes-Giannini MJS. Preliminary evaluation of circulating microRNAs as potential biomarkers in paracoccidioidomycosis. Biomed Rep. 2017 Mar;6(3):353-357. doi: 10.3892/br.2017.849. Epub 2017 Jan 26. PMID: 28451399; PMCID: PMC5403430.
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Biomed Rep. 2017 Mar;6(3):353-357. doi: 10.3892/br.2017.849. Epub 2017 Jan 26.

Preliminary evaluation of circulating microRNAs as potential biomarkers in paracoccidioidomycosis.

Biomedical reports

Junya De Lacorte Singulani, Julhiany De Fátima Da Silva, Fernanda Patricia Gullo, Marina Célia Costa, Ana Marisa Fusco-Almeida, Francisco Javier Enguita, Maria José Soares Mendes-Giannini

Affiliations

  1. Department of Clinical Analysis, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, São Paulo 14800-901, Brazil.
  2. Faculty of Medicine, Institute of Molecular Medicine, University of Lisbon, 1649-004 Lisbon, Portugal.

PMID: 28451399 PMCID: PMC5403430 DOI: 10.3892/br.2017.849

Abstract

MicroRNAs (miRNAs) are small RNAs (length, 19-24 nucleotides) that regulate gene expression by either mRNA degradation or translational inhibition of proteins. Circulating miRNAs, which are extremely stable and protected from RNAse-mediated degradation in body fluids, have appeared as candidate biomarkers for numerous diseases. However, little is known about circulating miRNAs in fungal infections. Paracoccidioidomycosis (PCM) is caused by the

Keywords: Paracoccidioides spp.; biological function; biomarker; microRNA; serum

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