Display options
Share it on

BMC Hematol. 2017 Apr 24;17:8. doi: 10.1186/s12878-017-0080-1. eCollection 2017.

Circumcision in hemophilia using low quantity of factor concentrates: experience from Dakar, Senegal.

BMC hematology

Moussa Seck, Aloïse Sagna, Mame Sokhna Guéye, Blaise Félix Faye, Diariétou Sy, Sokhna Aissatou Touré, Abibatou Sall, Awa Oumar Touré, Saliou Diop

Affiliations

  1. Hematology Service, Cheikh Anta Diop University, Dakar, BP 5005 Senegal.
  2. Pediatric Surgical Service, Cheikh Anta Diop University, Dakar, BP 5005 Senegal.
  3. Hematology Service, National Blood Transfusion Center, Dakar, BP 5005 Senegal.

PMID: 28451435 PMCID: PMC5402675 DOI: 10.1186/s12878-017-0080-1

Abstract

BACKGROUND: Circumcision in hemophiliacs is a delicate surgery because of bleeding risks that could be avoided by adequate substitution of coagulation factor. This practice is very challenging in countries where anti hemophilic treatment is inaccessible. The study aimed to evaluate a circumcision protocol in hemophilia A using low quantities of factor concentrates.

METHODS: This prospective study included 26 hemophiliacs A who underwent circumcision in 2014. Medical treatment protocol using low quantity of factor concentrates was drafted by physicians of the Hemophilia Treatment Center and the surgical protocol by experienced surgeons. Assessment criteria were: number of hospitalization days, number of exposure days to factor concentrates, delay to healing and occurrence of bleeding events.

RESULTS: Mean age was 9.6 years (1-30). Hemophiliacs patients were classified as severe (

CONCLUSION: The study shows treatment protocol using low quantity of factor concentrates is efficient in hemophilia patients who underwent circumcision.

Keywords: Bleeding complications; Circumcision; Hemophilia A

References

  1. BJU Int. 1999 Jan;83(1):91-4 - PubMed
  2. J Pediatr Surg. 2011 Feb;46(2):428-9 - PubMed
  3. Urol J. 2014 May 06;11(2):1406-10 - PubMed
  4. Med Sante Trop. 2013 Jan-Mar;23(1):111-2 - PubMed
  5. PLoS One. 2014 Mar 10;9(3):e91213 - PubMed
  6. Can J Urol. 2016 Apr;23 (2):8204-8 - PubMed
  7. Int J Emerg Med. 2015 Apr 10;8:8 - PubMed
  8. Haemophilia. 1998 Jan;4(1):1-3 - PubMed
  9. J Pak Med Assoc. 2010 Aug;60(8):664-7 - PubMed
  10. Arch Esp Urol. 2013 Nov;66(9):841-50 - PubMed
  11. Pediatr Hematol Oncol. 2012 Aug;29(5):485-93 - PubMed
  12. Haemophilia. 2014 Jan;20(1):73-7 - PubMed
  13. Urology. 2011 Jul;78(1):174-9 - PubMed
  14. Lijec Vjesn. 2007 Jun-Jul;129(6-7):241-6 - PubMed
  15. Haemophilia. 2010 Mar;16(2):272-6 - PubMed
  16. Urol Clin North Am. 2004 Aug;31(3):461-7, viii - PubMed
  17. Niger J Surg. 2012 Jul;18(2):71-4 - PubMed
  18. Haemophilia. 2013 May;19(3):e177-8 - PubMed
  19. Open Access J Urol. 2011 May 11;3:83-7 - PubMed
  20. BMC Urol. 2010 Feb 16;10:2 - PubMed
  21. Haemophilia. 2016 Jul;22 Suppl 5:36-41 - PubMed
  22. Br J Gen Pract. 2010 Mar;60(572):214-5; author reply 215 - PubMed
  23. Ann Fam Med. 2010 Jan-Feb;8(1):64-72 - PubMed
  24. Haemophilia. 2012 May;18(3):426-30 - PubMed
  25. Haemophilia. 2010 Nov;16(6):902-9 - PubMed
  26. Haemophilia. 2015 Jan;21(1):52-7 - PubMed
  27. J Public Health (Oxf). 2011 Jun;33(2):280-3 - PubMed
  28. Haemophilia. 2001 Sep;7(5):534-6 - PubMed
  29. Blood Coagul Fibrinolysis. 2011 Sep;22(6):547-8 - PubMed
  30. Haemophilia. 2010 Nov;16(6):888-91 - PubMed

Publication Types