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ESC Heart Fail. 2017 May;4(2):138-145. doi: 10.1002/ehf2.12128. Epub 2017 Jan 13.

Serum albumin level and hospital mortality in acute non-ischemic heart failure.

ESC heart failure

Arnaud Ancion, Sophie Allepaerts, Cécile Oury, Anne-Stephan Gori, Luc A Piérard, Patrizio Lancellotti

Affiliations

  1. University of Liège HospitalGIGA Cardiovascular Sciences, Acute Care Unit, Heart Failure Clinic, CHU Sart TilmanLiègeBelgium.
  2. University of Liège HospitalGeriatric Medicine, CHU Sart TilmanLiègeBelgium.
  3. Gruppo Villa Maria Care and ResearchAnthea HospitalBariItaly.

PMID: 28451450 PMCID: PMC5396050 DOI: 10.1002/ehf2.12128

Abstract

AIMS: Hypoalbuminemia is common in heart failure (HF), especially in elderly patients. It is associated with an increased risk of death. The present study sought to examine the prognostic significance of serum albumin level in the prediction of hospital mortality in patients admitted for acute non-ischemic HF.

METHODS AND RESULTS: We examined the association between albumin and hospital mortality in a cohort of 546 patients admitted for acute non-ischemic HF. None of the patients had infectious disease, severe arrhythmias (atrial fibrillation, ventricular tachycardia, ventricular fibrillation), required invasive ventilation, or presented with acute coronary syndrome or primary valvular disease. Thirty-six patients (7%) died during the hospital stay. These patients were significantly older (78 ± 9 vs. 72 ± 12 years;

CONCLUSIONS: Serum albumin level measured at admission can serve as a simple prognostic factor in acute non-ischemic HF. Hypoalbuminemia is associated with increased risk of hospital mortality, especially in elderly patients.

Keywords: Albumin; Heart failure; Hospital mortality; Outcome

References

  1. Arch Cardiovasc Dis. 2011 Oct;104(10):502-8 - PubMed
  2. Trends Immunol. 2010 Aug;31(8):318-24 - PubMed
  3. J Card Fail. 2015 Mar;21(3):179-88 - PubMed
  4. Rev Esp Cardiol (Engl Ed). 2014 Apr;67(4):277-82 - PubMed
  5. J Intern Med. 2007 Dec;262(6):678-89 - PubMed
  6. PLoS One. 2010 Aug 17;5(8):e12184 - PubMed
  7. JAMA. 2005 Feb 2;293(5):572-80 - PubMed
  8. Cardiovasc Res. 2010 Jul 15;87(2):331-9 - PubMed
  9. J Card Fail. 2011 Jun;17(6):451-8 - PubMed
  10. Int J Cardiol. 2015 Mar 1;182:426-30 - PubMed
  11. FEBS Lett. 2008 Jun 11;582(13):1783-7 - PubMed
  12. Am J Med Sci. 2010 Jan;339(1):31-5 - PubMed
  13. Ann Pharmacother. 2003 May;37(5):695-700 - PubMed
  14. Am J Cardiol. 2015 Feb 15;115(4):466-71 - PubMed
  15. Int J Cardiol. 2010 Apr 30;140(3):279-86 - PubMed
  16. Circulation. 2005 Sep 6;112(10):1428-34 - PubMed
  17. N Engl J Med. 2004 May 27;350(22):2247-56 - PubMed
  18. Eur J Heart Fail. 2012 Jan;14(1):39-44 - PubMed
  19. Eur J Heart Fail. 2011 Jul;13(7):765-72 - PubMed
  20. Circ Res. 1976 Sep;39(3):358-62 - PubMed
  21. Circulation. 2009 Nov 24;120(21):2040-5 - PubMed
  22. J Am Coll Cardiol. 2008 Jul 29;52(5):347-56 - PubMed
  23. Ital Heart J. 2003 Apr;4(4):232-5 - PubMed
  24. Eur Heart J. 2001 Sep;22(17):1527-60 - PubMed
  25. Intensive Care Med. 2011 Jan;37(1):86-96 - PubMed
  26. Eur Heart J. 2012 Feb;33(4):523-30 - PubMed
  27. ESC Heart Fail. 2017 May;4(2):138-145 - PubMed
  28. Lancet. 2008 Oct 4;372(9645):1223-30 - PubMed
  29. Am Heart J. 2006 Jan;151(1):76-83 - PubMed
  30. Int J Cardiol. 2013 Sep 30;168(2):1207-13 - PubMed
  31. Int J Cardiol. 2010 Dec 3;145(3):574-6 - PubMed
  32. Circulation. 2011 Jun 21;123(24):2829-37, 7 p following 2837 - PubMed
  33. J Am Coll Cardiol. 2003 Aug 20;42(4):712-6 - PubMed
  34. N Engl J Med. 2007 Aug 30;357(9):874-84 - PubMed
  35. Int J Cardiol. 2008 Apr 10;125(2):265-7 - PubMed
  36. J Card Fail. 2014 May;20(5):350-8 - PubMed
  37. Crit Care Med. 2005 Aug;33(8):1681-7 - PubMed
  38. Int J Cardiol. 2011 Feb 3;146(3):359-63 - PubMed

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