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Front Pharmacol. 2017 Apr 04;8:175. doi: 10.3389/fphar.2017.00175. eCollection 2017.

[No title available]

Frontiers in pharmacology

Hsing-Hui Su, Ya-Chun Chu, Jiuan-Miaw Liao, Yi-Hsin Wang, Ming-Shiou Jan, Chia-Wei Lin, Chiu-Yeh Wu, Chin-Yin Tseng, Jiin-Cherng Yen, Shiang-Suo Huang

Affiliations

  1. Institute of Pharmacology, National Yang-Ming UniversityTaipei, Taiwan.
  2. Department of Anesthesiology, Taipei Veterans General Hospital, National Yang-Ming UniversityTaipei, Taiwan.
  3. Department of Physiology, Chung Shan Medical University and Chung Shan Medical University HospitalTaichung, Taiwan.
  4. Institute of Medicine, Chung Shan Medical UniversityTaichung, Taiwan.
  5. Institute of Biochemistry, Microbiology and Immunology, Medical College, Chung Shan Medical UniversityTaichung, Taiwan.
  6. Division of Allergy, Immunology, and Rheumatology, Chung Shan Medical University HospitalTaichung, Taiwan.
  7. Immunology Research Center, Chung Shan Medical UniversityTaichung, Taiwan.
  8. Department of Culinary Arts, Chung Chou University of Science and TechnologyChanghua, Taiwan.
  9. Department of Health Food, Chung Chou University of Science and TechnologyChanghua, Taiwan.
  10. Department of Pharmacy, Chung Shan Medical University HospitalTaichung, Taiwan.
  11. Department of Pharmacology, Chung Shan Medical UniversityTaichung, Taiwan.

PMID: 28420993 PMCID: PMC5378821 DOI: 10.3389/fphar.2017.00175

Abstract

The incidence of myocardial ischemia-reperfusion (IR) injury is rapidly increasing around the world and this disease is a major contributor to global morbidity and mortality. It is known that regulation of programmed cell death including apoptosis and autophagy reduces the impact of myocardial IR injury. In this study, the cardioprotective effects and underlying mechanisms of

Keywords: Phellinus linteus; apoptosis; autophagy; cardioprotection; myocardial ischemia-reperfusion

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