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Allodi MA, Dahlberg PD, Mazuski RJ, et al. Optical resonance imaging: An optical analog to MRI with sub-diffraction-limited capabilities. ACS Photonics. 2016;3(12):2445-2452doi: 10.1021/acsphotonics.6b00694.
Allodi, M. A., Dahlberg, P. D., Mazuski, R. J., Davis, H. C., Otto, J. P., & Engel, G. S. (2016). Optical resonance imaging: An optical analog to MRI with sub-diffraction-limited capabilities. ACS photonics, 3(12), 2445-2452. https://doi.org/10.1021/acsphotonics.6b00694
Allodi, Marco A, et al. "Optical resonance imaging: An optical analog to MRI with sub-diffraction-limited capabilities." ACS photonics vol. 3,12 (2016): 2445-2452. doi: https://doi.org/10.1021/acsphotonics.6b00694
Allodi MA, Dahlberg PD, Mazuski RJ, Davis HC, Otto JP, Engel GS. Optical resonance imaging: An optical analog to MRI with sub-diffraction-limited capabilities. ACS Photonics. 2016 Dec 21;3(12):2445-2452. doi: 10.1021/acsphotonics.6b00694. Epub 2016 Nov 08. PMID: 28451625; PMCID: PMC5403159.
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ACS Photonics. 2016 Dec 21;3(12):2445-2452. doi: 10.1021/acsphotonics.6b00694. Epub 2016 Nov 08.

Optical resonance imaging: An optical analog to MRI with sub-diffraction-limited capabilities.

ACS photonics

Marco A Allodi, Peter D Dahlberg, Richard J Mazuski, Hunter C Davis, John P Otto, Gregory S Engel

Affiliations

  1. Department of Chemistry, The Institute for Biophysical Dynamics, The James Franck Institute, The University of Chicago, Chicago, IL, 60637, USA.
  2. Graduate Program in Biophysical Sciences, The University of Chicago, Chicago, IL, 60637, USA.

PMID: 28451625 PMCID: PMC5403159 DOI: 10.1021/acsphotonics.6b00694

Abstract

We propose here optical resonance imaging (ORI), a direct optical analog to magnetic resonance imaging (MRI). The proposed pulse sequence for ORI maps space to time and recovers an image from a heterodyne-detected third-order nonlinear photon echo measurement. As opposed to traditional photon echo measurements, the third pulse in the ORI pulse sequence has significant pulse-front tilt that acts as a temporal gradient. This gradient couples space to time by stimulating the emission of a photon echo signal from different lateral spatial locations of a sample at different times, providing a widefield ultrafast microscopy. We circumvent the diffraction limit of the optics by mapping the lateral spatial coordinate of the sample with the emission time of the signal, which can be measured to high precision using interferometric heterodyne detection. This technique is thus an optical analog of MRI, where magnetic-field gradients are used to localize the spin-echo emission to a point below the diffraction limit of the radio-frequency wave used. We calculate the expected ORI signal using 15 fs pulses and 87° of pulse-front tilt, collected using

Keywords: Exciton Imaging; Pulse-front Tilt; Spectral Interferometry; Superresolution Imaging; Ultrafast Microscopy

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