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Case Rep Oncol. 2017 Apr 04;10(1):308-315. doi: 10.1159/000464280. eCollection 2017.

Neoadjuvant Chemotherapy and Adjuvant Chemoradiation Therapy in the Treatment of Resected Gastric Adenocarcinoma: A Case Series.

Case reports in oncology

Christina Hadzitheodorou, Rebecca A Moss, Timothy J Kennedy, Salma K Jabbour

Affiliations

  1. aDepartment of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Rutgers Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ, USA.
  2. bDivision of Medical Oncology, Rutgers Cancer Institute of New Jersey, Rutgers University, New Brunswick, NJ, USA.
  3. cBristol-Myers Squibb, Global Clinical Research, Lawrence Township, NJ, USA.
  4. dDivision of Surgical Oncology, Rutgers Cancer Institute of New Jersey, Rutgers Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ, USA.

PMID: 28512415 PMCID: PMC5422732 DOI: 10.1159/000464280

Abstract

The treatment of gastric cancer requires a multimodal approach to decrease the risk of locoregional and distant recurrence. The optimal timing of chemotherapy, surgery, and radiation therapy continues to be explored in ongoing trials. In the United States, surgical resection is often followed by adjuvant chemoradiation therapy or by a combination of neoadjuvant and adjuvant chemotherapy. Here we report on 4 patients with resected gastric adenocarcinoma who were treated with a combination of these 2 approaches, receiving neoadjuvant chemotherapy followed by adjuvant chemoradiation therapy.

Keywords: Adjuvant therapy; Chemoradiation; Chemotherapy; Gastric cancer; Neoadjuvant therapy

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