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Friedman SN, Cunningham IA. Sci-Sat AM(1): Imaging-07: Open field normalization: How to avoid inflation to MTF and DQE values caused by zero-frequency normalization. Med Phys. 2008;35(7):3415doi: 10.1118/1.2965991.
Friedman, S. N., & Cunningham, I. A. (2008). Sci-Sat AM(1): Imaging-07: Open field normalization: How to avoid inflation to MTF and DQE values caused by zero-frequency normalization. Medical physics, 35(7), 3415. https://doi.org/10.1118/1.2965991
Friedman, S N, and Cunningham, I A. "Sci-Sat AM(1): Imaging-07: Open field normalization: How to avoid inflation to MTF and DQE values caused by zero-frequency normalization." Medical physics vol. 35,7 (2008): 3415. doi: https://doi.org/10.1118/1.2965991
Friedman SN, Cunningham IA. Sci-Sat AM(1): Imaging-07: Open field normalization: How to avoid inflation to MTF and DQE values caused by zero-frequency normalization. Med Phys. 2008 Jul;35(7):3415. doi: 10.1118/1.2965991. PMID: 28512872.
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Med Phys. 2008 Jul;35(7):3415. doi: 10.1118/1.2965991.

Sci-Sat AM(1): Imaging-07: Open field normalization: How to avoid inflation to MTF and DQE values caused by zero-frequency normalization.

Medical physics

S N Friedman, I A Cunningham

Affiliations

  1. Robarts Research Institute and The University of Western Ontario.
  2. London Health Sciences Centre, London, ON.

PMID: 28512872 DOI: 10.1118/1.2965991

Abstract

PURPOSE: To show that the novel open-field normalization technique prevents a common error in calculation of the detective quantum efficiency (DQE) caused by zero-frequency normalization of the modulation transfer function (MTF).

METHOD AND MATERIALS: Models describing zero-frequency and open-field normalization were used to derive the resulting measured MTF, noise power spectrum (NPS) and DQE using a finite region of interest (ROI) of image data. Simulated one-dimensional images containing Gaussian blur were used to model a deterministic system and to calculate the resultant values. Measurements were made using both zero-frequency and open-field normalization with ROIs ranging in size from 1-10 cm.

RESULTS: Use of a finite ROI results in truncation of the system line-spread function (LSF) causing the zero-frequency value of the measured MTF to be less than the true MTF value of unity, and causes spectral leakage in both the MTF and NPS. Zero-frequency normalization of the MTF inflates values at all non-zero frequencies. Since no zero-frequency normalization is performed on the NPS, this causes inflated DQE values. Simulated results show a 6% inflation of DQE values for a ROI of 10 cm, which increases as the ROI is reduced. Open-field normalization accurately determines MTF and NPS (and thus DQE) values at all frequencies away from zero frequency.

CONCLUSION: Open-field normalization measurements provide a good estimate of the true MTF and DQE. This approach should be used to avoid a common error in DQE calculations that is not obvious and inflates DQE calculations by 5-20%.

© 2008 American Association of Physicists in Medicine.

Keywords: Modulation transfer functions

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