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S Afr J Infect Dis. 2017;32(1):23-28. doi: 10.1080/22201181.2016.1201935. Epub 2016 Jun 29.

Relationship between HIV serostatus, CD4 count and rehospitalisation: Potential implications for health systems strengthening in South Africa.

Southern African journal of infectious diseases

Yoshan Moodley, Andrew Tomita

Affiliations

  1. Discipline of Anaesthesiology and Critical Care Medicine, University of KwaZulu-Natal, Durban, South Africa.
  2. Africa Centre for Health and Population Studies, University of KwaZulu-Natal, Durban, South Africa.

PMID: 28393071 PMCID: PMC5384337 DOI: 10.1080/22201181.2016.1201935

Abstract

BACKGROUND: Despite three decades of scientific response to HIV/AIDS, the generalised HIV epidemic continues to persist in South Africa. There is growing acknowledgement that health system strengthening will be critical in tackling HIV/AIDS. Patient rehospitalisation is an important quality benchmark of health service delivery, but there is currently limited data on rehospitalisation of patients with HIV/AIDS in South Africa, a setting with a high burden of HIV disease.

OBJECTIVES: To determine the relationship between combined HIV serostatus and CD4 count, and rehospitalisation in South Africa.

METHODS: This study was a retrospective analysis of data from 11,362 non-surgical adult patients who attended the Hlabisa Hospital in South Africa. Data related to patient age, gender, HIV serostatus, CD4 count (for HIV-positive patients) and comorbidity were analysed through univariate (Fisher's Exact or χ

RESULTS: An HIV-positive serostatus with CD4 count < 350 cells/mm

CONCLUSIONS: HIV-positive individuals with immune deficiency, or lacking a CD4 count measurement are at risk of rehospitalisation. Strengthening primary healthcare service delivery of these key affected inpatient populations should be a priority.

Keywords: CD4 count; HIV; patient re-admission; rehospitalisation; serostatus

Conflict of interest statement

Conflicts of Interest – None declared.

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