S Afr J Infect Dis. 2017;32(1):23-28. doi: 10.1080/22201181.2016.1201935. Epub 2016 Jun 29.
Relationship between HIV serostatus, CD4 count and rehospitalisation: Potential implications for health systems strengthening in South Africa.
Southern African journal of infectious diseases
Yoshan Moodley, Andrew Tomita
Affiliations
Affiliations
- Discipline of Anaesthesiology and Critical Care Medicine, University of KwaZulu-Natal, Durban, South Africa.
- Africa Centre for Health and Population Studies, University of KwaZulu-Natal, Durban, South Africa.
PMID: 28393071
PMCID: PMC5384337 DOI: 10.1080/22201181.2016.1201935
Abstract
BACKGROUND: Despite three decades of scientific response to HIV/AIDS, the generalised HIV epidemic continues to persist in South Africa. There is growing acknowledgement that health system strengthening will be critical in tackling HIV/AIDS. Patient rehospitalisation is an important quality benchmark of health service delivery, but there is currently limited data on rehospitalisation of patients with HIV/AIDS in South Africa, a setting with a high burden of HIV disease.
OBJECTIVES: To determine the relationship between combined HIV serostatus and CD4 count, and rehospitalisation in South Africa.
METHODS: This study was a retrospective analysis of data from 11,362 non-surgical adult patients who attended the Hlabisa Hospital in South Africa. Data related to patient age, gender, HIV serostatus, CD4 count (for HIV-positive patients) and comorbidity were analysed through univariate (Fisher's Exact or χ
RESULTS: An HIV-positive serostatus with CD4 count < 350 cells/mm
CONCLUSIONS: HIV-positive individuals with immune deficiency, or lacking a CD4 count measurement are at risk of rehospitalisation. Strengthening primary healthcare service delivery of these key affected inpatient populations should be a priority.
Keywords: CD4 count; HIV; patient re-admission; rehospitalisation; serostatus
Conflict of interest statement
Conflicts of Interest – None declared.
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