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Oncol Lett. 2017 Apr;13(4):2349-2353. doi: 10.3892/ol.2017.5692. Epub 2017 Feb 07.

miR-215 suppresses proliferation and migration of non-small cell lung cancer cells.

Oncology letters

Xiaopan Cai, Dongyu Peng, Haifeng Wei, Xinghai Yang, Quan Huang, Zaijun Lin, Wei Xu, Ming Qian, Cheng Yang, Tielong Liu, Wangjun Yan, Jian Zhao

Affiliations

  1. Department of Bone Tumor Surgery, Changzheng Hospital, The Second Military Medical University, Shanghai 200003, P.R. China.

PMID: 28454402 PMCID: PMC5403480 DOI: 10.3892/ol.2017.5692

Abstract

The expression of microRNA-215 (miR-215) in non-small cell lung cancer (NSCLC) tissues and the effects of miR-215 on the proliferation and migration of NSCLC cells were investigated. qRT-PCR was used to detect the expression of miR-215 in NSCLC tissues and paired normal tumor-adjacent lung tissues; MTT assay, transwell assay and soft-agar assay were used

Keywords: lung cancer; miR-215; microRNA; migration; non-small cell lung cancer

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