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Ronsard L, Ganguli N, Singh VK, et al. Impact of Genetic Variations in HIV-1 Tat on LTR-Mediated Transcription via TAR RNA Interaction. Front Microbiol. 2017;8:706doi: 10.3389/fmicb.2017.00706.
Ronsard, L., Ganguli, N., Singh, V. K., Mohankumar, K., Rai, T., Sridharan, S., Pajaniradje, S., Kumar, B., Rai, D., Chaudhuri, S., Coumar, M. S., Ramachandran, V. G., & Banerjea, A. C. (2017). Impact of Genetic Variations in HIV-1 Tat on LTR-Mediated Transcription via TAR RNA Interaction. Frontiers in microbiology, 8706. https://doi.org/10.3389/fmicb.2017.00706
Ronsard, Larance, et al. "Impact of Genetic Variations in HIV-1 Tat on LTR-Mediated Transcription via TAR RNA Interaction." Frontiers in microbiology vol. 8 (2017): 706. doi: https://doi.org/10.3389/fmicb.2017.00706
Ronsard L, Ganguli N, Singh VK, Mohankumar K, Rai T, Sridharan S, Pajaniradje S, Kumar B, Rai D, Chaudhuri S, Coumar MS, Ramachandran VG, Banerjea AC. Impact of Genetic Variations in HIV-1 Tat on LTR-Mediated Transcription via TAR RNA Interaction. Front Microbiol. 2017 Apr 21;8:706. doi: 10.3389/fmicb.2017.00706. eCollection 2017. PMID: 28484443; PMCID: PMC5399533.
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Front Microbiol. 2017 Apr 21;8:706. doi: 10.3389/fmicb.2017.00706. eCollection 2017.

Impact of Genetic Variations in HIV-1 Tat on LTR-Mediated Transcription via TAR RNA Interaction.

Frontiers in microbiology

Larance Ronsard, Nilanjana Ganguli, Vivek K Singh, Kumaravel Mohankumar, Tripti Rai, Subhashree Sridharan, Sankar Pajaniradje, Binod Kumar, Devesh Rai, Suhnrita Chaudhuri, Mohane S Coumar, Vishnampettai G Ramachandran, Akhil C Banerjea

Affiliations

  1. Laboratory of Virology, National Institute of ImmunologyDelhi, India.
  2. Department of Microbiology, University College of Medical Sciences and Guru Teg Bahadur HospitalDelhi, India.
  3. Centre for Bioinformatics, School of Life Sciences, Pondicherry UniversityPondicherry, India.
  4. Department of Biochemistry and Molecular Biology, Pondicherry UniversityPondicherry, India.
  5. Department of Veterinary Physiology and Pharmacology, Texas A&M University, College StationTX, USA.
  6. Department of Gastroenterology and Human Nutrition, All India Institute of Medical SciencesDelhi, India.
  7. Department of Symptom Research, The University of Texas MD Anderson Cancer Center, HoustonTX, USA.
  8. Department of Microbiology and Immunology, Rosalind Franklin University of Medicine and Science, ChicagoIL, USA.
  9. Department of Microbiology, All India Institute of Medical SciencesDelhi, India.
  10. Department of Neurological Surgery, Northwestern University, ChicagoIL, USA.

PMID: 28484443 PMCID: PMC5399533 DOI: 10.3389/fmicb.2017.00706

Abstract

HIV-1 evades host defense through mutations and recombination events, generating numerous variants in an infected patient. These variants with an undiminished virulence can multiply rapidly in order to progress to AIDS. One of the targets to intervene in HIV-1 replication is the

Keywords: HIV-1 Tat; TAR RNA; genetic variations; mutations; recombination; transactivation

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