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White GZ, Cox EL, Schwartz EJ, et al. Rare Solitary Fibrous Tumor in the Pediatric Neck: A Case Report and Review of the Literature. Cureus. 2017;9(4):e1140doi: 10.7759/cureus.1140.
White, G. Z., Cox, E. L., Schwartz, E. J., & Korkigian, S. A. (2017). Rare Solitary Fibrous Tumor in the Pediatric Neck: A Case Report and Review of the Literature. Cureus, 9(4), e1140. https://doi.org/10.7759/cureus.1140
White, G Zachary, et al. "Rare Solitary Fibrous Tumor in the Pediatric Neck: A Case Report and Review of the Literature." Cureus vol. 9,4 (2017): e1140. doi: https://doi.org/10.7759/cureus.1140
White GZ, Cox EL, Schwartz EJ, Korkigian SA. Rare Solitary Fibrous Tumor in the Pediatric Neck: A Case Report and Review of the Literature. Cureus. 2017 Apr 06;9(4):e1140. doi: 10.7759/cureus.1140. PMID: 28484679; PMCID: PMC5419818.
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Cureus. 2017 Apr 06;9(4):e1140. doi: 10.7759/cureus.1140.

Rare Solitary Fibrous Tumor in the Pediatric Neck: A Case Report and Review of the Literature.

Cureus

G Zachary White, Eric L Cox, Erich J Schwartz, Shant A Korkigian

Affiliations

  1. Otolaryngology/Facial Plastic Surgery, Beaumont Health- Farmington Hills.
  2. Otolaryngology, Michigan State University College of Osteopathic Medicine.
  3. Pathology, Beaumont Health.

PMID: 28484679 PMCID: PMC5419818 DOI: 10.7759/cureus.1140

Abstract

Solitary fibrous tumors (SFT) are a rare type of mesenchymal-derived tumor not commonly found in the pediatric population, especially in the head and neck. Tumors of this nature are most commonly seen in the adult population and are identified with unique immunohistochemical markers, specifically signal transducer and activator of transcription 6 (STAT6) and hematopoietic progenitor cell antigen (CD34). Including SFTs in the differential diagnosis while working up a mass can be difficult considering their relatively non-descript appearance on imaging and the low yield immunohistochemical staining that must be ordered to confirm diagnosis. The current literature identifies only a handful of cases of SFTs occurring in the pediatric population, with a majority arising from the pleura. We present the case of a 13-year-old male who underwent radical excision of a left occipital triangle neck mass after radiological and pathological workup failed to conclusively make a diagnosis. Postoperative pathologic analysis revealed it to be an SFT. Due to the exceptionally rare presentation of SFTs in pediatric patients, the aim of this case report is to discuss diagnostic measures, solitary fibrous tumor etiology, as well as a recent risk stratification system used for the evaluation of postoperative disease progression. Our hope is that clinicians will include SFTs in their differential diagnosis when working up a neck mass in the pediatric population.

Keywords: oncology; otolaryngology; pediatric; pediatric otolaryngology; pediatric surgery; rare tumor; solitary fibrous tumour

Conflict of interest statement

The authors have declared that no competing interests exist.

References

  1. Radiol Med. 2014 Dec;119(12 ):910-9 - PubMed
  2. AJR Am J Roentgenol. 2010 Jul;195(1):W55-62 - PubMed
  3. Jpn J Clin Oncol. 2014 Oct;44(10 ):926-31 - PubMed
  4. Am J Surg Pathol. 2014 Apr;38(4):552-9 - PubMed
  5. Cancer. 2002 Feb 15;94(4):1057-68 - PubMed
  6. Mod Pathol. 2012 Sep;25(9):1298-306 - PubMed
  7. J Neurosurg Pediatr. 2013 Jan;11(1):79-81 - PubMed
  8. Mod Pathol. 2014 Mar;27(3):390-5 - PubMed
  9. Ann Thorac Surg. 2012 Aug;94(2):394-400 - PubMed

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