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Indian J Psychol Med. 2017 Mar-Apr;39(2):209-212. doi: 10.4103/0253-7176.203130.

Delayed Stevens-Johnson Syndrome Secondary to the Use of Lamotrigine in Bipolar Mood Disorder.

Indian journal of psychological medicine

Kunal Kishor Jha, Durgesh Prasad Chaudhary, Tshristi Rijal, Semanta Dahal

Affiliations

  1. Department of Critical Care Medicine, Geisinger Medical Center, Danville, PA 17821, USA.
  2. Department of Internal Medicine, Norvic International Hospital, Kathmandu, Nepal.
  3. Dental Surgeon, Oracare Periodontal Clinic, Kathamandu, Nepal.
  4. Department of Internal Medicine Possible Health, Achham, Nepal.

PMID: 28515564 PMCID: PMC5385756 DOI: 10.4103/0253-7176.203130

Abstract

Lamotrigine is a mood-stabilizing drug used in maintenance treatment of bipolar I disease. There are adverse effects with lamotrigine such as a headache, blurred vision, diplopia, somnolence, ataxia, dizziness, rash, Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis. SJS is a life-threatening, blistering mucocutaneous disease. SJS is characterized by the presence of flat, diffuse erythematous maculopapular rashes with the involvement of <10% of the body surface area. Standard trigger is drugs including anticonvulsants, antibiotics, and

Keywords: Bipolar mood disorder; Steven–Johnson syndrome; delayed skin reactions; lamotrigine

Conflict of interest statement

There are no conflicts of interest.

References

  1. Epilepsia. 2004 May;45(5):410-23 - PubMed
  2. Allergy. 2007 Dec;62(12):1439-44 - PubMed
  3. Allergy. 2002 Jan;57(1):45-51 - PubMed
  4. Pediatr Emerg Care. 2016 Jul;32(7):472-6 - PubMed
  5. Front Pharmacol. 2015 Oct 23;6:242 - PubMed
  6. Eur Rev Med Pharmacol Sci. 2015;19(14):2732-7 - PubMed
  7. Allergy. 2004 Nov;59(11):1153-60 - PubMed
  8. Br J Dermatol. 2013 Nov;169(5):1071-80 - PubMed
  9. Expert Rev Clin Immunol. 2011 Nov;7(6):803-13; quiz 814-5 - PubMed
  10. Neurology. 2005 Apr 12;64(7):1134-8 - PubMed

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