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Hemodial Int. 2002 Jan;6(1):9-14. doi: 10.1111/hdi.2002.6.1.9.

The Middle Molecule Hypothesis Revisited. Should Short, Three Times Weekly Hemodialysis Be Abandoned?.

Hemodialysis international. International Symposium on Home Hemodialysis

Bernard Charra, Belding H Scribner, Zbylut J Twardowski, Jonas Bergström

Affiliations

  1. Centre de rein de Tassin, Centre de rein artificiel, Tassin, France.
  2. University of Washington, Seattle, Washington, U.S.A.
  3. University of Missouri, Columbia, Missouri, U.S.A.
  4. Division of Baxter Novum and Renal Medicine, Department of Clinical Science, Karolinska Institute, Huddinge Hospital, Stockholm, Sweden.

PMID: 28455930 DOI: 10.1111/hdi.2002.6.1.9

Abstract

When the middle molecule (MM) hypothesis was formulated in 1975, no MM had yet been identified as a uremic toxin. Meanwhile, the birth and implementation of the Kt/V

Keywords: Middle molecules; adequate dialysis; daily hemo dialysis; nocturnal hemodialysis; phosphate

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