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Front Plant Sci. 2017 Mar 27;8:403. doi: 10.3389/fpls.2017.00403. eCollection 2017.

Inactivation of the β(1,2)-xylosyltransferase and the α(1,3)-fucosyltransferase genes in .

Frontiers in plant science

Sébastien Mercx, Nicolas Smargiasso, François Chaumont, Edwin De Pauw, Marc Boutry, Catherine Navarre

Affiliations

  1. Institut des Sciences de la Vie, Université catholique de Louvain Louvain-la-Neuve, Belgium.
  2. Mass Spectrometry Laboratory, Molecular Systems Research Unit, Université de Liège Liège, Belgium.

PMID: 28396675 PMCID: PMC5366340 DOI: 10.3389/fpls.2017.00403

Abstract

Plants or plant cells can be used to produce pharmacological glycoproteins such as antibodies or vaccines. However these proteins carry

Keywords: antibody; gene editing; glyco-engineering; glycoproteins; humanized N-glycosylation; molecular farming; plant-specific glycans; suspension cells

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