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Front Nutr. 2017 Mar 27;4:10. doi: 10.3389/fnut.2017.00010. eCollection 2017.

Egg Consumption and Incidence of Heart Failure: A Meta-Analysis of Prospective Cohort Studies.

Frontiers in nutrition

Owais Khawaja, Hemindermeet Singh, Faraz Luni, Ameer Kabour, Syed S Ali, Mohammed Taleb, Hafeezuddin Ahmed, John Michael Gaziano, Luc Djoussé

Affiliations

  1. Department of Cardiology, Mercy St. Vincent Medical Center , Toledo, OH , USA.
  2. Division of Aging, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Massachusetts Veterans Epidemiology and Research Information Center (MAVERIC), Boston Veterans Affairs Healthcare System, Boston, MA, USA; Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Geriatric Research, Education, and Clinical Center (GRECC), Boston Veterans Affairs Healthcare System, Boston, MA, USA.
  3. Division of Aging, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Geriatric Research, Education, and Clinical Center (GRECC), Boston Veterans Affairs Healthcare System, Boston, MA, USA.

PMID: 28396858 PMCID: PMC5367008 DOI: 10.3389/fnut.2017.00010

Abstract

INTRODUCTION: Heart failure (HF) remains a major health problem affecting 5.7 million adults in USA. Data on the association of egg consumption with incident HF have been inconsistent. We, therefore, conducted this meta-analysis of prospective cohort studies to assess the relation of egg consumption with incident HF in the general population.

METHODS: Using extensive online search, we conducted a meta-analysis of new onset HF following exposure to egg consumption. A random effects model was used and between studies heterogeneity was estimated with

RESULTS: We identified four prospective cohorts for a total of 105,999 subjects and 5,059 cases of new onset HF. When comparing the highest (≥1/day) to the lowest category of egg consumption, pooled relative risk of HF was 1.25 (95% confidence interval = 1.12-1.39;

CONCLUSION: Our meta-analysis suggests an elevated risk of incident HF with frequent egg consumption.

Keywords: diet; eggs; epidemiology; heart failure; nutrition

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