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Med Phys. 2012 Jun;39(6):3661. doi: 10.1118/1.4734875.

SU-E-J-40: Lung Lesion Tracking Using Fixed-Spaced Non-Migrating Fiducial Markers in Robotic Radiosurgery.

Medical physics

J Gersh, K Reynolds, M DeWeese

Affiliations

  1. Mid-South Radiation Physics, Paragould, AR.
  2. IBA Dosimetry America, Memphis, TN.

PMID: 28517593 DOI: 10.1118/1.4734875

Abstract

PURPOSE: With lung lesion treatment being a major indication of the use of the CyberKnife (CK) robotic radiosurgery system (Accuray Inc, Sunnyvale, CA), the ability for the CK's stereoscopic kV imaging system to accurately track implanted fiducial markers becomes vital in the accurate delivery of therapeutic radiation. This study examines a novel fixed-space fiducial marker delivery system which is capable of delivering two VISICOIL (IBA Dosimetry America, Memphis, TN) non-migrating fiducial markers simultaneously at a fixed spacing through a single 20-gauge needle. More specifically, presented herein is a preliminary study which tests the CK'streatment localization system's (TLS) ability to track markers of varying size and spacing, comparing subsequent stereoscopic kV imaging to DRR's generated during the planning stages.

METHODS: Three markers were placed in an XLT Lung Phantom (CIRS Inc, Norfolk, VA); two markers inserted along a diagonal line in a coronal plane, separated by biocompatible spacersof varying size, and a common third marker being placed in a non-varyinglocation in a coronal plane anterior to the marker pair. This third marker allows the calculation of rotational and translation corrections. Differentcombinations were scanned, planned, and simulated; 3.5mm- and 5.0mm- long markers, each 5mm in diameter, were separated by 15mm, 17mm, and 20mm spacers.

RESULTS: The TLS system was able to track each of the aforementioned configurations with standard lung imaging parameters.Longer markers were not included in the study since earlier studies showed that without the natural deformation that would occur upon implantation, the length would induce false tracking.

CONCLUSIONS: This is a necessary firststep in determining the minimum spacing with which the CK's TLS can track, a study which can now proceed with the use of phantom treatments elivered to orthogonally-overlapping radiochromic film, bisecting a tumor volume which is implanted with this fiducial marker system. Research supported in-part by IBA Dosimetry America.

© 2012 American Association of Physicists in Medicine.

Keywords: Biocompatibility; Cancer; Dosimetry; Drug delivery; Lungs; Medical imaging; Radiation treatment; Radiosurgery; Robotics; Therapeutics

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