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Sidhu SK, Malhotra S, Devi P, et al. Significance of coagulase negative . Iran J Microbiol. 2016;8(6):366-371
Sidhu, S. K., Malhotra, S., Devi, P., & Tuli, A. K. (2016). Significance of coagulase negative . Iranian journal of microbiology, 8(6), 366-371.
Sidhu, Shailpreet K, et al. "Significance of coagulase negative ." Iranian journal of microbiology vol. 8,6 (2016): 366-371.
Sidhu SK, Malhotra S, Devi P, Tuli AK. Significance of coagulase negative . Iran J Microbiol. 2016 Dec;8(6):366-371. PMID: 28491246; PMCID: PMC5420390.
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Iran J Microbiol. 2016 Dec;8(6):366-371.

Significance of coagulase negative .

Iranian journal of microbiology

Shailpreet K Sidhu, Sita Malhotra, Pushpa Devi, Arpandeep K Tuli

Affiliations

  1. Department of Microbiology, Govt Medical College, Amritsar, Punjab, India.

PMID: 28491246 PMCID: PMC5420390

Abstract

BACKGROUND AND OBJECTIVES: Coagulase negative

MATERIALS AND METHODS: A retrospective study was conducted to evaluate the rate of contamination in blood cultures in a tertiary care hospital. The paired specimens of blood were cultured using conventional culture methods and the isolates of coagulase negative staphylococci were identified by standard methodology. Clinical data, laboratory indices, microbiological parameters and patient characteristics were analyzed.

RESULTS: Of 3503 blood samples, CoNS were isolated from blood culture of 307 patients (8.76%). The isolates were reported as true pathogens of bloodstream infections in only 74 out of 307 cases (24.1%). In the vast majority, 212 of 307 (69.0%), they were mere blood culture contaminants and reported as insignificant/contaminant.

CONCLUSION: Determining whether a growth in the blood culture is a pathogen or a contaminant is a critical issue and multiple parameters have to be considered before arriving at a conclusion. Ideally, the molecular approach is for the most part a consistent method in determining the significant isolates of CoNS. However, in countries with inadequate resources, species identification and antibiogram tests are recommended when determining significance of these isolates.

Keywords: Bloodstream infections; Coagulase negative Staphylococcus; Contaminants

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