Display options
Share it on

Transplant Direct. 2017 May 12;3(6):e162. doi: 10.1097/TXD.0000000000000679. eCollection 2017 Jun.

Kidney Transplant Recipients' Perspectives on Cardiovascular Disease and Related Risk Factors After Transplantation: A Qualitative Study.

Transplantation direct

Fabián Ballesteros, Julie Allard, Céline Durand, Héloïse Cardinal, Lyne Lalonde, Marie-Chantal Fortin

Affiliations

  1. Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Canada.
  2. Canadian National Transplant Research Program, Canada.
  3. Transplant and Nephrology Division, Centre Hospitalier de l'Université de Montréal (CHUM), Montréal, Canada.
  4. Faculty of Pharmacy, Université de Montréal, Montréal, Canada.

PMID: 28620646 PMCID: PMC5464781 DOI: 10.1097/TXD.0000000000000679

Abstract

BACKGROUND: Cardiovascular disease (CVD) is a major cause of mortality among kidney transplant recipients (KTRs). These patients have a high prevalence of risk factors, such as hypertension, diabetes, and dyslipidemia. Despite regular medical care, few of them reach the recommended therapeutic targets. The objective of this study is to describe KTRs' perspectives on CVD and related risk factors, as well as their priorities for posttransplant care.

METHODS: Twenty-six KTRs participated in a semistructured interview about their personal experience and offered their perspectives on CVD risk factors posttransplant. The interview was digitally recorded and the transcripts were analyzed using a thematic and content methodology.

RESULTS: CVD and related risk factors appear to be underestimated and trivialized. Only 2 of 26 patients identified CVD prevention and treatment as a priority. The most important posttransplant priorities identified by patients were related to immunosuppressive drugs (13 of 26), posttransplant follow-up (10) and graft survival (9). However, 21 of 26 patients stated they wanted to be better informed about posttransplant CVD risk factors.

CONCLUSIONS: CVD and related risk factors are not a priority for KTRs, and the importance of CVD is underestimated and trivialized. KTRs did recommend that tailored information be provided by various professionals and at several points in the transplantation process. This knowledge will help us develop a new approach to increase awareness of posttransplant CVD and related risk factors.

Conflict of interest statement

The author declares no conflicts of interest.

References

  1. Lancet. 2003 Jun 14;361(9374):2024-31 - PubMed
  2. Am J Kidney Dis. 2014 Jan;63(1 Suppl):A7 - PubMed
  3. Health Expect. 2009 Dec;12(4):396-406 - PubMed
  4. Transplant Proc. 1992 Aug;24(4):1583-4 - PubMed
  5. CMAJ. 2005 Nov 8;173(10):1181-4 - PubMed
  6. Transplant Proc. 2010 Nov;42(9):3578-85 - PubMed
  7. Ann Intern Med. 2012 Mar 20;156(6):416-24 - PubMed
  8. J Hum Hypertens. 2004 Dec;18(12):871-7 - PubMed
  9. Am J Kidney Dis. 2015 Aug;66(2):212-22 - PubMed
  10. Am J Transplant. 2009 Nov;9 Suppl 3:S1-155 - PubMed
  11. Am J Kidney Dis. 2004 Jun;43(6):1071-81 - PubMed
  12. Am J Kidney Dis. 2012 Aug;60(2):186-96 - PubMed
  13. PLoS One. 2015 Jun 24;10(6):e0131237 - PubMed
  14. J Gen Intern Med. 1998 Jan;13(1):32-8 - PubMed
  15. Am J Transplant. 2009 Aug;9(8):1811-5 - PubMed
  16. Circulation. 2011 Apr 26;123(16):1763-70 - PubMed
  17. Nephrol Dial Transplant. 2004 Jun;19 Suppl 3:iii62-6 - PubMed
  18. Lancet. 2011 Oct 15;378(9800):1419-27 - PubMed
  19. J Am Soc Nephrol. 2000 Apr;11(4):753-9 - PubMed
  20. J Am Soc Nephrol. 1994 Feb;4(8 Suppl):S30-6 - PubMed
  21. PLoS One. 2016 Sep 13;11(9):e0162725 - PubMed
  22. Am J Transplant. 2003 Feb;3(2):178-85 - PubMed

Publication Types