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Jeon HS, Hyon JY. Unilateral Posterior Polymorphous Corneal Dystrophy Presented as Anisometropic Astigmatism: 3 Case Reports. Case Rep Ophthalmol. 2017;8(1):250-258doi: 10.1159/000472704.
Jeon, H. S., & Hyon, J. Y. (2017). Unilateral Posterior Polymorphous Corneal Dystrophy Presented as Anisometropic Astigmatism: 3 Case Reports. Case reports in ophthalmology, 8(1), 250-258. https://doi.org/10.1159/000472704
Jeon, Hyun Sun, and Hyon, Joon Young. "Unilateral Posterior Polymorphous Corneal Dystrophy Presented as Anisometropic Astigmatism: 3 Case Reports." Case reports in ophthalmology vol. 8,1 (2017): 250-258. doi: https://doi.org/10.1159/000472704
Jeon HS, Hyon JY. Unilateral Posterior Polymorphous Corneal Dystrophy Presented as Anisometropic Astigmatism: 3 Case Reports. Case Rep Ophthalmol. 2017 Apr 21;8(1):250-258. doi: 10.1159/000472704. eCollection 2017. PMID: 28559836; PMCID: PMC5437481.
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Case Rep Ophthalmol. 2017 Apr 21;8(1):250-258. doi: 10.1159/000472704. eCollection 2017.

Unilateral Posterior Polymorphous Corneal Dystrophy Presented as Anisometropic Astigmatism: 3 Case Reports.

Case reports in ophthalmology

Hyun Sun Jeon, Joon Young Hyon

Affiliations

  1. aDepartment of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
  2. bDepartment of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.

PMID: 28559836 PMCID: PMC5437481 DOI: 10.1159/000472704

Abstract

BACKGROUND: Posterior polymorphous corneal dystrophy (PPCD) is typically considered bilateral and asymptomatic. However, few case reports on patients with unilateral PPCD with asymmetric refractive error have mentioned anisometropic amblyopia development. In support of this, we report 3 cases of unilateral PPCD that presented as anisometropic astigmatism. Visual prognosis related to amblyopia development is discussed.

CASE PRESENTATION: All 3 patients had a band lesion in the affected eye and a difference of at least 1.5 diopters in cylindrical refractive error between their eyes. The affected eye had a greater amount of astigmatism in all cases. Two patients (Cases 1 and 2) also had amblyopia in the affected eye. Case 1 was a 25-year-old male with a unilateral PPCD diagnosis and a band lesion involving the visual axis. Case 2 was an 11-year-old boy diagnosed with unilateral PPCD. The boy was treated with occlusion and atropine therapy over a 2-year period. Case 3 was a 4-year-old girl diagnosed with unilateral PPCD. The girl had a 30-month history of corrective spectacle use and had no amblyopia. In all cases, the corneal endothelial cell count was lower in the affected eye than in the unaffected contralateral eye.

CONCLUSIONS: Practitioners should closely monitor patients with unilateral PPCD for astigmatic anisometropia and amblyopia development. Visual prognosis for patients with unilateral PPCD may be related to lesion position, age at diagnosis, astigmatism severity, and early-childhood corrective spectacle use.

Keywords: Amblyopia; Anisometropia; Astigmatism; Corneal topography; Posterior polymorphous corneal dystrophy

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