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J Surg Case Rep. 2017 May 02;2017(5):rjx033. doi: 10.1093/jscr/rjx033. eCollection 2017 May.

Post-transplantation nephroptosis causing recurrent episodes of acute renal failure and hypertension secondary to intermittent vascular torsion of intraperitoneal renal allograft.

Journal of surgical case reports

Austin R Dosch, Madeleine Pahl, Uttam Reddy, Clarence E Foster, Hirohito Ichii

Affiliations

  1. Department of Surgery, University of California, Irvine School of Medicine, Irvine, CA, USA.
  2. Department of Medicine, University of California, Irvine School of Medicine, Irvine, CA, USA.

PMID: 28560019 PMCID: PMC5441242 DOI: 10.1093/jscr/rjx033

Abstract

Nephroptosis is a rare complication in renal transplantation, but one with significant associated risk. Due to non-specific clinical features, there may be a substantial delay in diagnosis and loss of the transplanted kidney due to renal pedicle thrombosis. We present a case of post-transplantation nephroptosis after simultaneous pancreas and kidney transplant, which resulted in accelerated hypertension and reversible acute kidney injury >1 year after transplantation. Prompt detection of this rare entity leading to expeditious surgical intervention is necessary to preserve viability of the renal allograft.

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