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Isomura S, Hashimoto R, Nakamura M, et al. Altered sulcogyral patterns of orbitofrontal cortex in a large cohort of patients with schizophrenia. NPJ Schizophr. 2017;3:3doi: 10.1038/s41537-016-0008-y.
Isomura, S., Hashimoto, R., Nakamura, M., Hirano, Y., Yamashita, F., Jimbo, S., Yamamori, H., Fujimoto, M., Yasuda, Y., Mears, R. P., & Onitsuka, T. (2017). Altered sulcogyral patterns of orbitofrontal cortex in a large cohort of patients with schizophrenia. NPJ schizophrenia, 33. https://doi.org/10.1038/s41537-016-0008-y
Isomura, Shuichi, et al. "Altered sulcogyral patterns of orbitofrontal cortex in a large cohort of patients with schizophrenia." NPJ schizophrenia vol. 3 (2017): 3. doi: https://doi.org/10.1038/s41537-016-0008-y
Isomura S, Hashimoto R, Nakamura M, Hirano Y, Yamashita F, Jimbo S, Yamamori H, Fujimoto M, Yasuda Y, Mears RP, Onitsuka T. Altered sulcogyral patterns of orbitofrontal cortex in a large cohort of patients with schizophrenia. NPJ Schizophr. 2017 Jan 12;3:3. doi: 10.1038/s41537-016-0008-y. eCollection 2017. PMID: 28560249; PMCID: PMC5441528.
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NPJ Schizophr. 2017 Jan 12;3:3. doi: 10.1038/s41537-016-0008-y. eCollection 2017.

Altered sulcogyral patterns of orbitofrontal cortex in a large cohort of patients with schizophrenia.

NPJ schizophrenia

Shuichi Isomura, Ryota Hashimoto, Motoaki Nakamura, Yoji Hirano, Fumio Yamashita, Shin Jimbo, Hidenaga Yamamori, Michiko Fujimoto, Yuka Yasuda, Ryan P Mears, Toshiaki Onitsuka

Affiliations

  1. Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashiku, Fukuoka, Japan.
  2. Molecular Research Center for Children's Mental Development, United Graduate School of Child Development, Osaka University, Osaka, Japan.
  3. Department of Psychiatry, Osaka University Graduate School of Medicine, Osaka, Japan.
  4. Kanagawa Psychiatric Center, Kanagawa, Japan.
  5. Division of Ultra-high Field MRI, Institute for Biomedical Sciences, Iwate Medical University, Iwate, Japan.
  6. Department of Psychology, University of Florida, Gainesville, FL USA.

PMID: 28560249 PMCID: PMC5441528 DOI: 10.1038/s41537-016-0008-y

Abstract

Abnormalities in prenatal brain development contribute to schizophrenia vulnerability. Orbitofrontal cortex sulcogyral patterns are largely determined during prenatal development, and four types of orbitofrontal cortex sulcogyral patterns have been classified in humans. Altered orbitofrontal cortex patterns have been reported in individuals with schizophrenia using magnetic resonance imaging; however, sample sizes of previous studies were small-medium effects for detection, and gender manifestation for orbitofrontal cortex sulcogyral patterns is unclear. The present study investigated orbitofrontal cortex patterns of 155 patients with schizophrenia and 375 healthy subjects. The orbitofrontal cortex sulcogyral pattern distributions of schizophrenia were significantly different compared with healthy subjects in the left hemisphere (

References

  1. Brain. 2007 Mar;130(Pt 3):693-707 - PubMed
  2. Schizophr Res. 2010 Aug;121(1-3):55-65 - PubMed
  3. Schizophr Res. 2014 Apr;154(1-3):93-9 - PubMed
  4. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jul 1;44:168-77 - PubMed
  5. Hum Brain Mapp. 2015 Mar;36(3):1138-50 - PubMed
  6. Brain. 1997 Jun;120 ( Pt 6):1057-65 - PubMed
  7. Ann Neurol. 1977 Jan;1(1):86-93 - PubMed
  8. Psychiatry Clin Neurosci. 2011 Aug;65(5):483-9 - PubMed
  9. Prog Neuropsychopharmacol Biol Psychiatry. 2014 Jun 3;51:166-71 - PubMed
  10. Transl Psychiatry. 2014 Oct 21;4:e472 - PubMed

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