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Kumar P, Swami D, Karade HN, et al. Protection studies of new . Interdiscip Toxicol. 2017;9(3):101-105doi: 10.1515/intox-2016-0013.
Kumar, P., Swami, D., Karade, H. N., Singh, M., Tiwari, A., & Singh, K. P. (2016). Protection studies of new . Interdisciplinary toxicology, 9(3), 101-105. https://doi.org/10.1515/intox-2016-0013
Kumar, Pravin, et al. "Protection studies of new ." Interdisciplinary toxicology vol. 9,3 (2016): 101-105. doi: https://doi.org/10.1515/intox-2016-0013
Kumar P, Swami D, Karade HN, Singh M, Tiwari A, Singh KP. Protection studies of new . Interdiscip Toxicol. 2016 Dec;9(3):101-105. doi: 10.1515/intox-2016-0013. Epub 2017 May 17. PMID: 28652853; PMCID: PMC5464681.
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Interdiscip Toxicol. 2016 Dec;9(3):101-105. doi: 10.1515/intox-2016-0013. Epub 2017 May 17.

Protection studies of new .

Interdisciplinary toxicology

Pravin Kumar, Devyani Swami, Hitendra N Karade, Manindar Singh, Anupma Tiwari, Kshetra Pal Singh

Affiliations

  1. Pharmacology and Toxicology Division, Defence Research & Development Establishment, Jhansi Road, Gwalior, India.
  2. Process Technology Development Division, Defence Research & Development Establishment, Jhansi Road, Gwalior, India.
  3. Directorate of Life Science, DRDO Bhawan, Ministry of Defence, New Delhi, India.

PMID: 28652853 PMCID: PMC5464681 DOI: 10.1515/intox-2016-0013

Abstract

The available antidotal therapy against acute poisoning by organophosphates involves the use of atropine alone or in combination with one of the oximes, e.g. 2-PAM, Obidoxime, TMB-4 or HI-6. Each of these oximes has some limitation, raising the question of the universal antidotal efficacy against poisoning by all OPs/nerve agents. In the present study, newly synthesized

Keywords: 2-PAM; AChE reactivation; DDVP; HNK Oximes

Conflict of interest statement

The authors declare that there are no conflicts of interest.

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