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Am J Geriatr Psychiatry. 1996 Summer;4(3):252-257. doi: 10.1097/00019442-199622430-00009. Epub 2012 Aug 14.

Anxiety and Depression as Predictors of Recurrence in Geriatric Depression: A Preliminary Report.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Barnett S Meyers, Michelle Gabriele, Tatsu Kakuma, Laura Ippolito, George Alexopoulos

Affiliations

  1. New York Hospital-Cornell Medical Center, Westchester Division.

PMID: 28531084 DOI: 10.1097/00019442-199622430-00009

Abstract

The authors studied elderly patients with major depression (MDD) who recovered after nortriptyline treatment to determine the relationship of affective symptoms at completion of continuation treatment to eventual MDD recurrence. Independent objective measures of depressive and anxiety symptoms were obtained before and after nortriptyline tapering. Univariate log-rank analysis demonstrated a trend for total post-discontinuation anxiety scores to predict time-to-recurrence in 12 subjects with complete data sets. Items assessing excessive worry and psychic tension (subjective anxiety) were significant predictors. No relationship was found between continuation-phase anxiety or depressive symptoms either immediately preceding or after discontinuation and course.

Copyright © 1996 American Association for Geriatric Psychiatry. Published by Elsevier Inc. All rights reserved.

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