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Virus Evol. 2017 May 24;3(1):vex013. doi: 10.1093/ve/vex013. eCollection 2017 Jan.

Rising prevalence of non-B HIV-1 subtypes in North Carolina and evidence for local onward transmission.

Virus evolution

Ann M Dennis, Stephane Hué, Emily Learner, Joseph Sebastian, William C Miller, Joseph J Eron

Affiliations

  1. Division of Infectious Diseases, University of North Carolina, Chapel Hill, NC, USA.
  2. London School of Hygiene & Tropical Medicine, London, UK.
  3. Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.
  4. Laboratory Corporation of America, Research Triangle Park, NC, USA.
  5. Department of Epidemiology, Ohio State University, Columbus, OH, USA.

PMID: 28567304 PMCID: PMC5442504 DOI: 10.1093/ve/vex013

Abstract

HIV-1 diversity is increasing in North American and European cohorts which may have public health implications. However, little is known about non-B subtype diversity in the southern United States, despite the region being the epicenter of the nation's epidemic. We characterized HIV-1 diversity and transmission clusters to identify the extent to which non-B strains are transmitted locally. We conducted cross-sectional analyses of HIV-1 partial

Keywords: HIV-1; molecular epidemiology; southeastern United States; transmission

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