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Martínez MA, Ares I, Rodríguez JL, et al. Oral Bioavailability and Plasma Disposition of Pefloxacin in Healthy Broiler Chickens. Front Vet Sci. 2017;4:77doi: 10.3389/fvets.2017.00077.
Martínez, M. A., Ares, I., Rodríguez, J. L., Martínez, M., Martínez-Larrañaga, M. R., Isea, G., & Anadón, A. (2017). Oral Bioavailability and Plasma Disposition of Pefloxacin in Healthy Broiler Chickens. Frontiers in veterinary science, 477. https://doi.org/10.3389/fvets.2017.00077
Martínez, María-Aránzazu, et al. "Oral Bioavailability and Plasma Disposition of Pefloxacin in Healthy Broiler Chickens." Frontiers in veterinary science vol. 4 (2017): 77. doi: https://doi.org/10.3389/fvets.2017.00077
Martínez MA, Ares I, Rodríguez JL, Martínez M, Martínez-Larrañaga MR, Isea G, Anadón A. Oral Bioavailability and Plasma Disposition of Pefloxacin in Healthy Broiler Chickens. Front Vet Sci. 2017 May 24;4:77. doi: 10.3389/fvets.2017.00077. eCollection 2017. PMID: 28596959; PMCID: PMC5442175.
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Front Vet Sci. 2017 May 24;4:77. doi: 10.3389/fvets.2017.00077. eCollection 2017.

Oral Bioavailability and Plasma Disposition of Pefloxacin in Healthy Broiler Chickens.

Frontiers in veterinary science

María-Aránzazu Martínez, Irma Ares, José-Luis Rodríguez, Marta Martínez, María-Rosa Martínez-Larrañaga, Gerardo Isea, Arturo Anadón

Affiliations

  1. Department of Toxicology and Pharmacology, Faculty of Veterinary Medicine, Universidad Complutense de Madrid, Madrid, Spain.

PMID: 28596959 PMCID: PMC5442175 DOI: 10.3389/fvets.2017.00077

Abstract

The pharmacokinetics of pefloxacin after single 10 mg/kg BW intravenous (IV) and oral doses were studied in healthy broiler chickens. For 24 h, serial blood samples were obtained after IV and oral administration. Concentrations of pefloxacin and its major metabolite

Keywords: IV and oral dose; PK/PD modeling; broiler chickens; kinetics; pefloxacin

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