Display options
Cite
Acosta S, Torres V, Paulos M, et al. CLOVES Syndrome: Severe Neonatal Presentation. J Clin Diagn Res. 2017;11(4):TR01-TR03doi: 10.7860/JCDR/2017/23801.9719.
Acosta, S., Torres, V., Paulos, M., & Cifuentes, I. (2017). CLOVES Syndrome: Severe Neonatal Presentation. Journal of clinical and diagnostic research : JCDR, 11(4), TR01-TR03. https://doi.org/10.7860/JCDR/2017/23801.9719
Acosta, Silvana, et al. "CLOVES Syndrome: Severe Neonatal Presentation." Journal of clinical and diagnostic research : JCDR vol. 11,4 (2017): TR01-TR03. doi: https://doi.org/10.7860/JCDR/2017/23801.9719
Acosta S, Torres V, Paulos M, Cifuentes I. CLOVES Syndrome: Severe Neonatal Presentation. J Clin Diagn Res. 2017 Apr;11(4):TR01-TR03. doi: 10.7860/JCDR/2017/23801.9719. Epub 2017 Apr 01. PMID: 28571234; PMCID: PMC5449880.
Copy Download .nbib Format: NLM
Share it on

J Clin Diagn Res. 2017 Apr;11(4):TR01-TR03. doi: 10.7860/JCDR/2017/23801.9719. Epub 2017 Apr 01.

CLOVES Syndrome: Severe Neonatal Presentation.

Journal of clinical and diagnostic research : JCDR

Silvana Acosta, Viviana Torres, María Paulos, Ignacio Cifuentes

Affiliations

  1. Assistant Professor, Department of Plastic Surgery Section, Surgery Division, Medical School, Pontificia Universidad Católica de Chile, Santiago, Santiago, Chile.
  2. Surgeon, Department of Pediatric Surgery, Hospital Félix Bulnes, Santiago, Santiago, Chile.
  3. Surgeon, Department of Plastic Surgery Unit, Hospital de Niños Roberto del Río, Santiago, Santiago, Chile.
  4. Resident, Department of Plastic Surgery Section, Surgery Division, Medical School, Pontificia Universidad Católica de Chile, Santiago, Santiago, Chile.

PMID: 28571234 PMCID: PMC5449880 DOI: 10.7860/JCDR/2017/23801.9719

Abstract

Congenital Lipomatous Overgrowth, Vascular Malformations, Epidermal Nevi and Spinal Abnormalities (CLOVES syndrome) is a newly described and rare overgrowth disorder with serious morbidity. The course of this disease is not well understood and few cases have been reported among neonates. Moreover, not all of the signs of this syndrome are present at birth, making a high index of suspicion necessary. We present a cohort of three newborns with CLOVES syndrome who died due to septic and hemodynamic complications directly related to extensive vascular malformations. We discuss the clinical presentation in the neonatal period and propose a clinical classification.

Keywords: Lipodystrophy; Neonatal; Vascular malformation

References

  1. Am J Med Genet A. 2009 Feb;149A(2):294; author reply 295 - PubMed
  2. Am J Med Genet A. 2007 Dec 15;143A(24):2944-58 - PubMed
  3. Pediatr Dermatol. 2010 May-Jun;27(3):311-2 - PubMed
  4. J Thorac Cardiovasc Surg. 2010 Aug;140(2):459-63 - PubMed
  5. Am J Med Genet A. 2012 Jul;158A(7):1690-5 - PubMed
  6. Clin Dysmorphol. 2009 Jan;18(1):1-7 - PubMed
  7. Pediatr Radiol. 2010 Aug;40(8):1436-9 - PubMed
  8. Pediatr Dermatol. 2011 Mar-Apr;28(2):215-6 - PubMed
  9. AJNR Am J Neuroradiol. 2011 Nov-Dec;32(10):1812-7 - PubMed
  10. Am J Med Genet A. 2008 Oct 15;146A(20):2688-90 - PubMed

Publication Types