Display options
Cite
Janghorbani M, Salamat MR, Aminorroaya A, et al. Utility of the Visceral Adiposity Index and Hypertriglyceridemic Waist Phenotype for Predicting Incident Hypertension. Endocrinol Metab (Seoul). 2017;32(2):221-229doi: 10.3803/EnM.2017.32.2.221.
Janghorbani, M., Salamat, M. R., Aminorroaya, A., & Amini, M. (2017). Utility of the Visceral Adiposity Index and Hypertriglyceridemic Waist Phenotype for Predicting Incident Hypertension. Endocrinology and metabolism (Seoul, Korea), 32(2), 221-229. https://doi.org/10.3803/EnM.2017.32.2.221
Janghorbani, Mohsen, et al. "Utility of the Visceral Adiposity Index and Hypertriglyceridemic Waist Phenotype for Predicting Incident Hypertension." Endocrinology and metabolism (Seoul, Korea) vol. 32,2 (2017): 221-229. doi: https://doi.org/10.3803/EnM.2017.32.2.221
Janghorbani M, Salamat MR, Aminorroaya A, Amini M. Utility of the Visceral Adiposity Index and Hypertriglyceridemic Waist Phenotype for Predicting Incident Hypertension. Endocrinol Metab (Seoul). 2017 Jun;32(2):221-229. doi: 10.3803/EnM.2017.32.2.221. Epub 2017 May 19. PMID: 28537054; PMCID: PMC5503867.
Copy Download .nbib Format: NLM
Share it on

Endocrinol Metab (Seoul). 2017 Jun;32(2):221-229. doi: 10.3803/EnM.2017.32.2.221. Epub 2017 May 19.

Utility of the Visceral Adiposity Index and Hypertriglyceridemic Waist Phenotype for Predicting Incident Hypertension.

Endocrinology and metabolism (Seoul, Korea)

Mohsen Janghorbani, Mohammad Reza Salamat, Ashraf Aminorroaya, Masoud Amini

Affiliations

  1. Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. [email protected].
  2. Department of Medical Physics and Medical Engineering, Isfahan University of Medical Sciences, Isfahan, Iran.
  3. Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

PMID: 28537054 PMCID: PMC5503867 DOI: 10.3803/EnM.2017.32.2.221

Abstract

BACKGROUND: The aim of this study was to assess the utility of the visceral adiposity index (VAI) and the hypertriglyceridemic waist (HTGW) phenotype as possible hypertension (HTN) predictors in a high-risk population without diabetes and HTN.

METHODS: Incident HTN over a 7-year follow-up was assessed among 1,375 first-degree non-diabetic and non-hypertensive relatives of consecutive patients with type 2 diabetes who were 30 to 70 years of age. HTN was defined as a blood pressure reading ≥140/90 mm Hg or the use of antihypertensive medications. We examined the incidence of HTN across VAI quintiles and four groups defined according to baseline fasting serum triglyceride (TG) levels and waist circumference (WC).

RESULTS: The VAI and the HTGW phenotype at baseline were related to an increased risk for HTN. In comparison with the lowest VAI quintile, the highest VAI quintile showed a significant associated with HTN in an age- and gender-adjusted model (odds ratio [OR], 1.65; 95% confidence interval [CI], 1.07 to 2.55). Those with HTGW were 2.3 times (OR, 2.27; 95% CI, 1.54 to 3.35) more likely to develop HTN than those with a normal WC and normal TG levels.

CONCLUSION: Greater VAI values weakly predicted HTN, whereas the HTGW phenotype was a stronger predictor of incident HTN in an Iranian high-risk population.

Copyright © 2017 Korean Endocrine Society

Keywords: Hypertension; Hypertriglyceridemic waist; Incidence; Risk factors; Visceral adiposity index

Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

References

  1. Clin Chem. 1972 Jun;18(6):499-502 - PubMed
  2. Diabetes Care. 1995 Feb;18(2):174-81 - PubMed
  3. Obesity (Silver Spring). 2010 Jan;18(1):153-60 - PubMed
  4. J Diabetes Investig. 2016 Nov;7(6):860-866 - PubMed
  5. Ann Epidemiol. 1990 Oct;1(1):33-48 - PubMed
  6. Obes Res. 2000 Oct;8(7):516-24 - PubMed
  7. Circulation. 2003 Oct 7;108(14):1718-23 - PubMed
  8. Hypertens Res. 2011 May;34(5):565-72 - PubMed
  9. Stroke. 1990 May;21(5):701-6 - PubMed
  10. Am J Hypertens. 2008 Aug;21(8):910-6 - PubMed
  11. Hypertension. 1990 Nov;16(5):484-90 - PubMed
  12. Ann Intern Med. 2004 Jun 15;140(12):992-1000 - PubMed
  13. Int J Obes. 1990 Jun;14(6):515-25 - PubMed
  14. Diabetes Care. 2003 Jan;26 Suppl 1:S5-20 - PubMed
  15. Diabetes Care. 2013 Jan;36 Suppl 1:S4-10 - PubMed
  16. Rev Diabet Stud. 2007 Fall;4(3):169-76 - PubMed
  17. Diabetes Care. 2010 Apr;33(4):920-2 - PubMed
  18. Appl Physiol Nutr Metab. 2013 Aug;38(8):892-9 - PubMed
  19. JAMA. 2014 Feb 5;311(5):507-20 - PubMed
  20. Lancet. 2015 Aug 22;386(9995):801-12 - PubMed
  21. BMC Public Health. 2009 May 29;9:167 - PubMed
  22. Int J Obes Relat Metab Disord. 1992 Nov;16(11):881-90 - PubMed
  23. Circulation. 2007 Jul 3;116(1):39-48 - PubMed
  24. Can J Cardiol. 2007 Oct;23 Suppl B:23B-31B - PubMed
  25. Int J Obes Relat Metab Disord. 1998 Feb;22(2):127-34 - PubMed

Publication Types