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Adi-Dako O, Oppong Bekoe S, Ofori-Kwakye K, et al. Novel HPLC Analysis of Hydrocortisone in Conventional and Controlled-Release Pharmaceutical Preparations. J Pharm (Cairo). 2017;2017:9495732doi: 10.1155/2017/9495732.
Adi-Dako, O., Oppong Bekoe, S., Ofori-Kwakye, K., Appiah, E., & Peprah, P. (2017). Novel HPLC Analysis of Hydrocortisone in Conventional and Controlled-Release Pharmaceutical Preparations. Journal of pharmaceutics, 20179495732. https://doi.org/10.1155/2017/9495732
Adi-Dako, Ofosua, et al. "Novel HPLC Analysis of Hydrocortisone in Conventional and Controlled-Release Pharmaceutical Preparations." Journal of pharmaceutics vol. 2017 (2017): 9495732. doi: https://doi.org/10.1155/2017/9495732
Adi-Dako O, Oppong Bekoe S, Ofori-Kwakye K, Appiah E, Peprah P. Novel HPLC Analysis of Hydrocortisone in Conventional and Controlled-Release Pharmaceutical Preparations. J Pharm (Cairo). 2017;2017:9495732. doi: 10.1155/2017/9495732. Epub 2017 Jun 04. PMID: 28660092; PMCID: PMC5474276.
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J Pharm (Cairo). 2017;2017:9495732. doi: 10.1155/2017/9495732. Epub 2017 Jun 04.

Novel HPLC Analysis of Hydrocortisone in Conventional and Controlled-Release Pharmaceutical Preparations.

Journal of pharmaceutics

Ofosua Adi-Dako, Samuel Oppong Bekoe, Kwabena Ofori-Kwakye, Enoch Appiah, Paul Peprah

Affiliations

  1. Department of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana.
  2. Department of Pharmaceutics and Microbiology, School of Pharmacy, University of Ghana, Legon, Accra, Ghana.
  3. Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana.

PMID: 28660092 PMCID: PMC5474276 DOI: 10.1155/2017/9495732

Abstract

An isocratic sensitive and precise reverse phase high-performance liquid chromatography (RP-HPLC) method was developed and validated for the determination and quantification of hydrocortisone in controlled-release and conventional (tablets and injections) pharmaceutical preparations. Chromatographic separation was achieved on an ODS (C18), 5 

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