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Weerakkody D, Andreev OA, Reshetnyak YK. Insertion into lipid bilayer of truncated pHLIP. Biochem Biophys Rep. 2016;8:290-295doi: 10.1016/j.bbrep.2016.10.001.
Weerakkody, D., Andreev, O. A., & Reshetnyak, Y. K. (2016). Insertion into lipid bilayer of truncated pHLIP. Biochemistry and biophysics reports, 8290-295. https://doi.org/10.1016/j.bbrep.2016.10.001
Weerakkody, Dhammika, et al. "Insertion into lipid bilayer of truncated pHLIP." Biochemistry and biophysics reports vol. 8 (2016): 290-295. doi: https://doi.org/10.1016/j.bbrep.2016.10.001
Weerakkody D, Andreev OA, Reshetnyak YK. Insertion into lipid bilayer of truncated pHLIP. Biochem Biophys Rep. 2016 Dec;8:290-295. doi: 10.1016/j.bbrep.2016.10.001. Epub 2016 Oct 08. PMID: 28664189; PMCID: PMC5486998.
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Biochem Biophys Rep. 2016 Dec;8:290-295. doi: 10.1016/j.bbrep.2016.10.001. Epub 2016 Oct 08.

Insertion into lipid bilayer of truncated pHLIP.

Biochemistry and biophysics reports

Dhammika Weerakkody, Oleg A Andreev, Yana K Reshetnyak

Affiliations

  1. Department of Physics, University of Rhode Island, Kingston, RI 02881, United States.

PMID: 28664189 PMCID: PMC5486998 DOI: 10.1016/j.bbrep.2016.10.001

Abstract

The investigation of pH-dependent membrane-associated folding has both fundamental interest and practical applications for targeting of acidic tumors and specific delivery of therapeutic molecules across membrane of cancer cells. We and others investigated molecular mechanism and medical uses of class of water soluble membrane peptides, pH (Low) Insertion Peptides (pHLIP

Keywords: CD; Dual quenching; FRET; Fluorescence; OCD; Tumor targeting

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