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Hsiao CC, Weng CH, Li YJ, et al. Comparison of the clinical features and outcomes of infective endocarditis between hemodialysis and non-hemodialysis patients. Ther Clin Risk Manag. 2017;13:663-668doi: 10.2147/TCRM.S135262.
Hsiao, C. C., Weng, C. H., Li, Y. J., Wu, H. H., Chen, Y. C., Chen, Y. M., Hsu, H. H., & Tian, Y. C. (2017). Comparison of the clinical features and outcomes of infective endocarditis between hemodialysis and non-hemodialysis patients. Therapeutics and clinical risk management, 13663-668. https://doi.org/10.2147/TCRM.S135262
Hsiao, Ching-Chung, et al. "Comparison of the clinical features and outcomes of infective endocarditis between hemodialysis and non-hemodialysis patients." Therapeutics and clinical risk management vol. 13 (2017): 663-668. doi: https://doi.org/10.2147/TCRM.S135262
Hsiao CC, Weng CH, Li YJ, Wu HH, Chen YC, Chen YM, Hsu HH, Tian YC. Comparison of the clinical features and outcomes of infective endocarditis between hemodialysis and non-hemodialysis patients. Ther Clin Risk Manag. 2017 May 24;13:663-668. doi: 10.2147/TCRM.S135262. eCollection 2017. PMID: 28579790; PMCID: PMC5449118.
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Ther Clin Risk Manag. 2017 May 24;13:663-668. doi: 10.2147/TCRM.S135262. eCollection 2017.

Comparison of the clinical features and outcomes of infective endocarditis between hemodialysis and non-hemodialysis patients.

Therapeutics and clinical risk management

Ching-Chung Hsiao, Cheng-Hao Weng, Yi-Jung Li, Hsin-Hsu Wu, Yung-Chang Chen, Yu-Ming Chen, Hsiang-Hao Hsu, Ya-Chung Tian

Affiliations

  1. Kidney Research Center and Department of Nephrology, Chang Gung Memorial Hospital, Taipei.
  2. Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan.

PMID: 28579790 PMCID: PMC5449118 DOI: 10.2147/TCRM.S135262

Abstract

Hemodialysis (HD) patients are more susceptible to infective endocarditis (IE) due to the increased risk of bacterial invasion through intravascular access. However, it remains unclear whether the causative organisms and outcomes of IE in HD patients differ from those in non-HD patients. This study clarified the differences in clinical presentation and outcomes between HD and non-HD patients. At our hospital, we performed a retrospective study of 39 HD and 51 non-HD patients with echocardiography-confirmed IE between June 2000 and February 2007. No differences in sex, intravenous drug use, previous diagnosis of congestive heart failure, and previous valvular surgery were observed between these two groups. The number of patients with diabetic mellitus in these two groups was significantly different (28.2% HD vs 5.9% non-HD patients). The C-reactive protein levels in the two groups were not significantly different. By contrast, the erythrocyte sedimentation rate was significantly higher in the HD patients (HD vs non-HD: 87.2±33.32 vs 52.96±28.19). The incidence of IE involving the mitral valve (MV; 45.1%) or the aortic valve (AV; 43.1%) was similar among the non-HD patients, whereas a preference of IE involving the MV (79.5%) over the AV (15.4%) was noted among the HD patients. The HD patients had a significantly higher

Keywords: Staphylococcus aureus; aortic valve; hemodialysis; infective endocarditis; mitral valve

Conflict of interest statement

Disclosure The authors report no conflicts of interest in this work.

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