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Loreto ELS, Pereira CM. Somatizing the transposons action. Mob Genet Elements. 2017;7(3):1-9doi: 10.1080/2159256X.2017.1314236.
Loreto, E. L. S., & Pereira, C. M. (2017). Somatizing the transposons action. Mobile genetic elements, 7(3), 1-9. https://doi.org/10.1080/2159256X.2017.1314236
Loreto, Elgion L S, and Pereira, Camila Moura. "Somatizing the transposons action." Mobile genetic elements vol. 7,3 (2017): 1-9. doi: https://doi.org/10.1080/2159256X.2017.1314236
Loreto ELS, Pereira CM. Somatizing the transposons action. Mob Genet Elements. 2017 Apr 13;7(3):1-9. doi: 10.1080/2159256X.2017.1314236. eCollection 2017. PMID: 28580196; PMCID: PMC5443659.
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Mob Genet Elements. 2017 Apr 13;7(3):1-9. doi: 10.1080/2159256X.2017.1314236. eCollection 2017.

Somatizing the transposons action.

Mobile genetic elements

Elgion L S Loreto, Camila Moura Pereira

Affiliations

  1. Department of Biochemistry and Molecular Biology, University of Santa Maria, Santa Maria, RS, Brazil.
  2. Postgraduate Programme in Animal Biodiversity, University of Santa Maria, Santa Maria, RS, Brazil.

PMID: 28580196 PMCID: PMC5443659 DOI: 10.1080/2159256X.2017.1314236

Abstract

The somatic mobilization of transposable elements is more common than previously thought. In this review we discuss how the intensity and the biologic consequences of somatic mobilization are dependent on the transposable elements landscapes of each genome, and on the "momentum" of each particular TE with respect to the mechanisms that control its transposition and the possibility to escape this control. Additionally, the biologic consequences of somatic mobilization vary among organisms that show an early separation between the germline and somatic cells and those organisms that do not exhibit this separation or that reproduce asexually. In the former, somatic transposition can be involved in phenotypic plasticity, detrimental conditions such as disease, or processes such as aging. For the organisms without separation between the germ and soma, somatic mobilization can be a source of genetic variability.

Keywords: genetic mosaicism; somatic mobilization; somatic transposition; transposable elements

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