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Brehler M, Thawait G, Shyr W, et al. Atlas-based automatic measurements of the morphology of the tibiofemoral joint. Proc SPIE Int Soc Opt Eng. 2017;10137doi: 10.1117/12.2255566.
Brehler, M., Thawait, G., Shyr, W., Ramsay, J., Siewerdsen, J. H., & Zbijewski, W. (2017). Atlas-based automatic measurements of the morphology of the tibiofemoral joint. Proceedings of SPIE--the International Society for Optical Engineering, 10137. https://doi.org/10.1117/12.2255566
Brehler, M, et al. "Atlas-based automatic measurements of the morphology of the tibiofemoral joint." Proceedings of SPIE--the International Society for Optical Engineering vol. 10137 (2017). doi: https://doi.org/10.1117/12.2255566
Brehler M, Thawait G, Shyr W, Ramsay J, Siewerdsen JH, Zbijewski W. Atlas-based automatic measurements of the morphology of the tibiofemoral joint. Proc SPIE Int Soc Opt Eng. 2017 Feb 11;10137. doi: 10.1117/12.2255566. Epub 2017 Mar 13. PMID: 28638170; PMCID: PMC5475286.
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Proc SPIE Int Soc Opt Eng. 2017 Feb 11;10137. doi: 10.1117/12.2255566. Epub 2017 Mar 13.

Atlas-based automatic measurements of the morphology of the tibiofemoral joint.

Proceedings of SPIE--the International Society for Optical Engineering

M Brehler, G Thawait, W Shyr, J Ramsay, J H Siewerdsen, W Zbijewski

Affiliations

  1. Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD USA.
  2. Department of Radiology, Johns Hopkins University, Baltimore, MD USA.
  3. Natick Soldier Research, Development and Engineering Center (NSRDEC), Natick, MA USA.

PMID: 28638170 PMCID: PMC5475286 DOI: 10.1117/12.2255566

Abstract

PURPOSE: Anatomical metrics of the tibiofemoral joint support assessment of joint stability and surgical planning. We propose an automated, atlas-based algorithm to streamline the measurements in 3D images of the joint and reduce user-dependence of the metrics arising from manual identification of the anatomical landmarks.

METHODS: The method is initialized with coarse registrations of a set of atlas images to the fixed input image. The initial registrations are then refined separately for the tibia and femur and the best matching atlas is selected. Finally, the anatomical landmarks of the best matching atlas are transformed onto the input image by deforming a surface model of the atlas to fit the shape of the tibial plateau in the input image (a mesh-to-volume registration). We apply the method to weight-bearing volumetric images of the knee obtained from 23 subjects using an extremity cone-beam CT system. Results of the automated algorithm were compared to an expert radiologist for measurements of Static Alignment (SA), Medial Tibial Slope (MTS) and Lateral Tibial Slope (LTS).

RESULTS: Intra-reader variability as high as ~10% for LTS and 7% for MTS (ratio of standard deviation to the mean in repeated measurements) was found for expert radiologist, illustrating the potential benefits of an automated approach in improving the precision of the metrics. The proposed method achieved excellent registration of the atlas mesh to the input volumes. The resulting automated measurements yielded high correlations with expert radiologist, as indicated by correlation coefficients of 0.72 for MTS, 0.8 for LTS, and 0.89 for SA.

CONCLUSIONS: The automated method for measurement of anatomical metrics of the tibiofemoral joint achieves high correlation with expert radiologist without the need for time consuming and error prone manual selection of landmarks.

Keywords: atlas registration; cone-beam CT; extremities imaging; tibiofemoral joint

References

  1. J Bone Joint Surg Am. 2008 Dec;90(12 ):2724-34 - PubMed
  2. IEEE Trans Med Imaging. 2010 Jan;29(1):196-205 - PubMed
  3. Orthop Clin North Am. 1994 Jul;25(3):425-65 - PubMed
  4. Arthroscopy. 2006 Aug;22(8):894-9 - PubMed
  5. J Bone Joint Surg Br. 1994 Sep;76(5):745-9 - PubMed
  6. Radiology. 2014 Mar;270(3):816-24 - PubMed
  7. Am J Sports Med. 2010 Jan;38(1):54-62 - PubMed

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