Display options
Cite
Huang W, Shen F, Zhang J, et al. Effect of Repetitive Transcranial Magnetic Stimulation on Cigarette Smoking in Patients with Schizophrenia. Shanghai Arch Psychiatry. 2016;28(6):309-317doi: 10.11919/j.issn.1002-0829.216044.
Huang, W., Shen, F., Zhang, J., & Xing, B. (2016). Effect of Repetitive Transcranial Magnetic Stimulation on Cigarette Smoking in Patients with Schizophrenia. Shanghai archives of psychiatry, 28(6), 309-317. https://doi.org/10.11919/j.issn.1002-0829.216044
Huang, Wanli, et al. "Effect of Repetitive Transcranial Magnetic Stimulation on Cigarette Smoking in Patients with Schizophrenia." Shanghai archives of psychiatry vol. 28,6 (2016): 309-317. doi: https://doi.org/10.11919/j.issn.1002-0829.216044
Huang W, Shen F, Zhang J, Xing B. Effect of Repetitive Transcranial Magnetic Stimulation on Cigarette Smoking in Patients with Schizophrenia. Shanghai Arch Psychiatry. 2016 Dec 25;28(6):309-317. doi: 10.11919/j.issn.1002-0829.216044. PMID: 28638206; PMCID: PMC5434288.
Copy Download .nbib Format: NLM
Share it on

Shanghai Arch Psychiatry. 2016 Dec 25;28(6):309-317. doi: 10.11919/j.issn.1002-0829.216044.

Effect of Repetitive Transcranial Magnetic Stimulation on Cigarette Smoking in Patients with Schizophrenia.

Shanghai archives of psychiatry

Wanli Huang, Fang Shen, Jiangtao Zhang, Baoping Xing

Affiliations

  1. Tongde Hospital, Hangzhou, Zhejiang Province, China.

PMID: 28638206 PMCID: PMC5434288 DOI: 10.11919/j.issn.1002-0829.216044

Abstract

BACKGROUND: The high smoking rate among patients with schizophrenia is an important public health problem, and researchers have been studying how to change the status quo.

OBJECTIVE: We investigated the effects of high frequency (10Hz) repetitive transcranial magnetic stimulation on the amount of cigarette smoking in patients with schizophrenia.

METHOD: This study enrolled 37 male patients with schizophrenia who were at a stable stage of treatment. Patients were randomly divided into a treatment group (n=19) and a control group (n=18). The treatment group received repetitive transcranial magnetic stimulation (rTMS) on the left prefrontal dorsolateral cortex (DLPFC), and the control group received placebo treatment. The number of cigarettes smoked were recorded at 7 days before treatment, during the course of treatment (i.e. for 21 days), and 3 weeks after treatment had ended. Assessments using the Positive and Negative Syndrome Scale (PANSS), Wisconsin Card Sorting Test (WCST), and Montgomery Asberg Depression Rating Scale (MADRS) were applied before and after treatment.

RESULT: Compared to the control group, the number of cigarettes smoked in the treatment group showed a statistically significant reduction in the first week after treatment. However, there was no significant correlation between the scores on PANSS, WCST and MADRS and the number of cigarettes smoked before and after treatment in both groups.

DISCUSSION: High frequency (10Hz) repetitive transcranial magnetic stimulation on the left prefrontal cortex can reduce the number of cigarettes smoked in patients with schizophrenia.

Keywords: Repetitive transcranial magnetic stimulation; cigarette smoking; schizophrenia

References

  1. Biol Psychiatry. 1997 Jul 1;42(1):1-5 - PubMed
  2. Psychiatry Res. 2014 Mar 30;215(3):505-13 - PubMed
  3. Brain Stimul. 2013 May;6(3):221-30 - PubMed
  4. Brain. 2006 Jul;129(Pt 7):1659-73 - PubMed
  5. Eur J Pharmacol. 2000 Mar 30;393(1-3):295-314 - PubMed
  6. J Psychiatr Res. 2014 Mar;50:84-91 - PubMed
  7. Neurophysiol Clin. 2006 May-Jun;36(3):157-83 - PubMed
  8. Int Rev Neurobiol. 2015;124:23-78 - PubMed
  9. Biol Psychiatry. 2013 Apr 15;73(8):714-20 - PubMed
  10. Neuroimage. 2006 Aug 1;32(1):477-84 - PubMed
  11. PLoS One. 2012;7(2):e30937 - PubMed
  12. Exp Brain Res. 1998 Sep;122(1):79-84 - PubMed
  13. Schizophr Res. 2005 Jul 15;76(2-3):135-57 - PubMed
  14. J Neuropsychiatry Clin Neurosci. 2007 Fall;19(4):464-7 - PubMed
  15. PLoS One. 2014 Feb 10;9(2):e88478 - PubMed
  16. Psychiatry Res. 2003 Aug 30;120(1):103-5 - PubMed
  17. Schizophr Res. 2011 Apr;127(1-3):241-5 - PubMed
  18. Schizophr Res. 2012 Aug;139(1-3):264-6 - PubMed

Publication Types