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Kanar O, Berry AC, Nakshabendi R, et al. Effects of Immunomodulators and Biologic Agents on Sexual Health in Patients With Inflammatory Bowel Disease. Ochsner J. 2017;17(2):150-156
Kanar, O., Berry, A. C., Nakshabendi, R., Lee, A. J., Aldridge, P., Myers, T., & Eid, E. (2017). Effects of Immunomodulators and Biologic Agents on Sexual Health in Patients With Inflammatory Bowel Disease. The Ochsner journal, 17(2), 150-156.
Kanar, Ozdemir, et al. "Effects of Immunomodulators and Biologic Agents on Sexual Health in Patients With Inflammatory Bowel Disease." The Ochsner journal vol. 17,2 (2017): 150-156.
Kanar O, Berry AC, Nakshabendi R, Lee AJ, Aldridge P, Myers T, Eid E. Effects of Immunomodulators and Biologic Agents on Sexual Health in Patients With Inflammatory Bowel Disease. Ochsner J. 2017;17(2):150-156. PMID: 28638288; PMCID: PMC5472074.
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Ochsner J. 2017;17(2):150-156.

Effects of Immunomodulators and Biologic Agents on Sexual Health in Patients With Inflammatory Bowel Disease.

The Ochsner journal

Ozdemir Kanar, Andrew C Berry, Rahman Nakshabendi, Ann Joo Lee, Petra Aldridge, Travis Myers, Emely Eid

Affiliations

  1. Department of Internal Medicine, University of Florida-Jacksonville, Jacksonville, FL.
  2. Department of Internal Medicine, University of South Alabama, Mobile, AL.
  3. Division of Gastroenterology, Department of Medicine, University of Florida-Jacksonville, Jacksonville, FL.
  4. Department of Biostatistics, University of Florida-Jacksonville, Jacksonville, FL.
  5. Department of Performance Data, Wheaton Franciscan Healthcare, Glendale, WI.

PMID: 28638288 PMCID: PMC5472074

Abstract

BACKGROUND: Although much knowledge has been gained regarding the medical and surgical management of inflammatory bowel disease (IBD), a paucity of information is available on the psychosexual issues related to IBD. The aim of this study was to evaluate the sexual health of patients with IBD who were taking immunomodulators and/or biologic agents vs patients with IBD who were not on that medication regimen.

METHODS: All study participants completed a validated sexual health questionnaire, the Female Sexual Function Index or the International Index of Erectile Function, to assess their subjective perception of the effect of IBD on the different domains of sexual function during the prior 1-month time period.

RESULTS: No statistically significant differences in any baseline demographic variables were found for either sex between the group taking immunomodulators/biologic agents and the nontreatment group. Among females and males, individual question responses, domain scores, and total scores showed no statistically significant differences between the 2 treatment groups.

CONCLUSION: Our data suggest that the use of immunomodulators or biologic agents does not affect female or male sexual health. However, treatment of patients with IBD must be individualized based on the aggressive nature of the disease, treatment goals, and the tolerability of various medications.

Keywords: Adjuvants–immunologic; biological factors; inflammatory bowel diseases; reproductive health

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