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Interv Cardiol Clin. 2014 Jul;3(3):393-404. doi: 10.1016/j.iccl.2014.03.009. Epub 2014 Jun 28.

Intravenous and Oral Hydration: Approaches, Principles, and Differing Regimens.

Interventional cardiology clinics

Igor Rojkovskiy, Richard Solomon

Affiliations

  1. Division of Nephrology and Hypertension, Fletcher Allen Health Care, University of Vermont College of Medicine, UHC 2309, 1 South Prospect Street, Burlington, VT 05401, USA.
  2. Division of Nephrology and Hypertension, Fletcher Allen Health Care, University of Vermont College of Medicine, UHC 2309, 1 South Prospect Street, Burlington, VT 05401, USA. Electronic address: [email protected].

PMID: 28582224 DOI: 10.1016/j.iccl.2014.03.009

Abstract

Prevention of contrast-induced nephropathy is founded on minimizing the pathophysiologic consequences of contrast media (CM) interacting with a vulnerable kidney. In this article, the rationale for administering fluid (oral or intravenous) is discussed, and the clinical trials exploring different protocols are reviewed. A benefit from administration of fluids before CM exposure, which corrects volume depletion and increases urine output, can be expected. Forced diuresis without adequate volume replacement is deleterious.

Copyright © 2014 Elsevier Inc. All rights reserved.

Keywords: Bicarbonate; Contrast-induced nephropathy; Forced diuresis; Furosemide; Saline

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