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Sharma B, Singh H, Chodhary P, et al. Osteoporosis in Otherwise Healthy Patients with Type 2 Diabetes: A Prospective Gender Based Comparative Study. Indian J Endocrinol Metab. 2017;21(4):535-539doi: 10.4103/ijem.IJEM_108_17.
Sharma, B., Singh, H., Chodhary, P., Saran, S., & Mathur, S. K. (2017). Osteoporosis in Otherwise Healthy Patients with Type 2 Diabetes: A Prospective Gender Based Comparative Study. Indian journal of endocrinology and metabolism, 21(4), 535-539. https://doi.org/10.4103/ijem.IJEM_108_17
Sharma, Balram, et al. "Osteoporosis in Otherwise Healthy Patients with Type 2 Diabetes: A Prospective Gender Based Comparative Study." Indian journal of endocrinology and metabolism vol. 21,4 (2017): 535-539. doi: https://doi.org/10.4103/ijem.IJEM_108_17
Sharma B, Singh H, Chodhary P, Saran S, Mathur SK. Osteoporosis in Otherwise Healthy Patients with Type 2 Diabetes: A Prospective Gender Based Comparative Study. Indian J Endocrinol Metab. 2017 Jul-Aug;21(4):535-539. doi: 10.4103/ijem.IJEM_108_17. PMID: 28670536; PMCID: PMC5477440.
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Indian J Endocrinol Metab. 2017 Jul-Aug;21(4):535-539. doi: 10.4103/ijem.IJEM_108_17.

Osteoporosis in Otherwise Healthy Patients with Type 2 Diabetes: A Prospective Gender Based Comparative Study.

Indian journal of endocrinology and metabolism

Balram Sharma, Hema Singh, Praveen Chodhary, Sanjay Saran, Sandeep Kumar Mathur

Affiliations

  1. Department of Endocrinology, SMS Medical College and Hospitals, Jaipur, Rajasthan, India.

PMID: 28670536 PMCID: PMC5477440 DOI: 10.4103/ijem.IJEM_108_17

Abstract

BACKGROUND AND OBJECTIVE: Type 2 diabetes mellitus (T2DM) may affect bone loss differentially in adult males and postmenopausal females. We evaluated the prevalence of osteoporosis in otherwise healthy adults with T2DM.

MATERIALS AND METHODS: In a cross-sectional study, adults with T2DM, aged 50 years and above, were evaluated for bone mineral density (BMD) using dual-energy X-ray absorptiometry (DXA) scan at spine and hip. T-score of ≤-2.5 was defined as osteoporosis and score -2.49 to -1.0 as osteopenia at either site. Correlation of low BMD with demographic, clinical, and laboratory parameters including serum Vitamin D and serum testosterone (in males) was evaluated.

RESULTS: In 200 patients, mean age was 64.5 ± 7.0 years and age differed significantly in males and females (

CONCLUSION: Prevalence of osteoporosis in otherwise healthy T2DM was 35.5% with greater prevalence in females than males. Body mass but not Vitamin D or testosterone has an important role in the determination of bone loss in T2DM.

Keywords: Bone mineral density; Type 2 diabetes mellitus; osteoporosis; sex

Conflict of interest statement

There are no conflicts of interest.

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